What is the distance between Panama City and Key West?

The distance between the two cities is 455 miles (733 km).

What are the departure and arrival stations when taking the bus from Panama City to Key West?

If you're headed to Key West from Panama City, chances are that your bus will depart from Panama City Greyhound Bus Station and arrive at Caroline St. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Key West?

Once in Key West, you can start exploring the city and discover its surroundings. The top sights and things to do are Fort Zachary Taylor State Park Beach, Mallory Square, Florida Keys Eco-Discovery Center, Key West Lighthouse & Keeper’s Quarters Museum and Fury Water Adventure.

Bus Panama City to Key West from $128 | Refundable Tickets

Previously seen trips

Next departures for Panama City to Key West on November 8
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	12:50pm	Panama City Beach Station	1d 1h	3:30pm	Key West Bus Station	No tags
Greyhound + FlixBus	12:50pm	Panama City Beach Station	22h 10m	12:00pm	Caroline St	No tags
Greyhound + FlixBus	12:50pm	Panama City Beach Station	1d 1h	3:30pm	Key West Bus Station	No tags
FlixBus + Greyhound	12:50pm	Panama City Beach Station	22h 10m	12:00pm	Caroline St	No tags
Greyhound + FlixBus	12:50pm	Panama City Beach Station	22h 10m	12:00pm	Caroline St	No tags

Get from Panama City to Key West

This route is served by bus only

The journey takes about 1 day, 1 hour 40 minutes and with fares starting at just $128, it presents an excellent value for a comfortable ride.

2bus per day

1d 1hAverage Duration

460 milesDistance

19kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,358 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Panama City and Key West?

Stops in Panama City

A - Panama City Greyhound Bus Station

Stops in Key West

A - Caroline St

B - EYW Airport

Frequently asked questions about traveling from Panama City, US to Key West by bus

What is the distance between Panama City and Key West?
What are the departure and arrival stations when taking the bus from Panama City to Key West?
What are the best sights and things to do in Key West?

Top traveled bus routes

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