Bus Tickets from Panama City, US to Jacksonville, FL

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TodayJun 28
TomorrowJun 29
from $58
MonJun 30
from $53
TueJul 1
from $48
WedJul 2
from $53
ThuJul 3
from $63
FriJul 4
SatJul 5

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 29 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: June 29 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Panama City to Jacksonville: Trip Overview

Average ticket price$49
Average bus trip duration6h 45m
Number of daily buses1
Earliest bus departure12:50pm
Distance245 miles (394 km)

Panama City to Jacksonville Bus

With Busbud, comparing and booking tickets for a bus from Panama City to Jacksonville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Panama City to Jacksonville will be provided by the most trusted bus companies.

Discover how much the bus trip from Panama City to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Panama City, US - Jacksonville, FL

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/26
No data
06/27
$43
Today
$57
06/29
$50
06/30
$45
07/01
$40
07/02
$45
07/03
$55
busbud logoThe cheapest trip from Panama City to Jacksonville was searched and found on Jul 1, 2025 with a price of $40

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City to Jacksonville, as early as possible.

You can expect to pay from $40 to $57 for a bus ticket from Panama City to Jacksonville based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2025-07-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Panama City to Jacksonville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Panama City to Jacksonville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Panama City to Jacksonville will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Jacksonville.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Panama City by bus?

Bus from Panama City to Jacksonville

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