What is the distance between Panama City and Jacksonville?

About 240 miles (387 km) separate Panama City and Jacksonville.

What are the departure and arrival stations when taking the bus from Panama City to Jacksonville?

If you're headed to Jacksonville from Panama City, chances are that your bus will leave from Panama City Greyhound Bus Station and arrive at W Forsyth St. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

Bus Panama City to Jacksonville from $43 | Refundable Tickets

Previously seen trips

Next departures for Panama City to Jacksonville on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:50pm	Panama City Beach Station	6h 45m	8:35pm	Jacksonville Bus Station	No tags
Bus	12:50pm	Panama City Beach Station	6h 45m	8:35pm	Jacksonville Bus Station	No tags
Bus	12:50pm	Panama City Beach Station	6h 45m	8:35pm	Jacksonville Bus Station	No tags
Bus	12:50pm	Panama City Beach Station	6h 45m	8:35pm	Jacksonville Bus Station	No tags
Bus	12:50pm	Panama City Beach Station	6h 45m	8:35pm	Jacksonville Bus Station	No tags

Get from Panama City to Jacksonville

This route is served by bus only

The journey takes about 6 hours 45 minutes and with fares starting at just $38, it presents an excellent value for a comfortable ride.

2bus per day

6h 45mAverage Duration

245 milesDistance

10kgCO₂ emissions

Where are the popular stops in Panama City and Jacksonville?

Stops in Panama City

A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401

Stops in Jacksonville

A
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
B
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
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C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Compare bus companies

Greyhound

3.5/587,392 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Panama City, US to Jacksonville, FL by bus

What is the distance between Panama City and Jacksonville?
What are the departure and arrival stations when taking the bus from Panama City to Jacksonville?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

$80

11/22

$77

Today

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The cheapest trip from Panama City, US to Jacksonville, FL was searched and found on Nov 22, 2025 with a price of $77

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Jacksonville, FL, as early as possible.