Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Jacksonville Bus Station | Cheapest | ||||
| Bus | Panama City Beach Station | Jacksonville Bus Station | Fastest |
Last refresh of the prices: Last Saturday at 3:02 PM CST.
Get from Panama City to Jacksonville
The journey takes about 6 hours 45 minutes, and with fares starting at just R 662, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87382 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 662
Where are the popular stops in Panama City and Jacksonville?
Frequently asked questions about travelling from Panama City, US to Jacksonville, FL by bus
How much does a bus ticket from Panama City to Jacksonville cost?
The bus ticket price from Panama City to Jacksonville starts at R 662. The best way to find cheap bus tickets from Panama City to Jacksonville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Panama City to Jacksonville?
The average travel time between Panama City and Jacksonville is around 6h 45m, although the fastest bus will take about 6h 45m. This is the time it takes to travel the 387 km that separates the two cities.
How many daily bus connections are there between Panama City and Jacksonville?
The number of buses from Panama City to Jacksonville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Panama City to Jacksonville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Panama City to Jacksonville?
When taking the bus from Panama City to Jacksonville, you can travel comfortably and safely with Greyhound.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Jacksonville, FL was searched and found on 17 Nov 2025 with a price of R 918To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Jacksonville, FL as early as possible.
You can expect to pay from R 918 to R 1 818 for a bus ticket from Panama City, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 165, which is on 2025-11-21.
