Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Jacksonville Bus Station | Cheapest | ||||
| Bus | Panama City Beach Station | Jacksonville Bus Station | Fastest |
Last refresh of the prices: Today at 4:58 AM CST.
Get from Panama City to Jacksonville
The journey takes about 6 hours 45 minutes, and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Jacksonville?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Based on 87401 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $68
Frequently asked questions about travelling from Panama City, US to Jacksonville, FL by bus
What is the distance between Panama City and Jacksonville?
The distance covered from Panama City to Jacksonville is 387 km (240 miles).
What are the departure and arrival locations for buses traveling from Panama City to Jacksonville?
Buses traveling this route start their trip at Panama City Greyhound Bus Station, in Panama City, and end it at Jacksonville Amtrak Station, in Jacksonville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Jacksonville, FL was searched and found on Nov 28, 2025 with a price of $95To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Jacksonville, FL, as early as possible.
You can expect to pay from $95 to $187 for a bus ticket from Panama City, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $95 which is on 2025-11-28.
