Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Jacksonville Bus Station | Cheapest | ||||
| Bus | Panama City Beach Station | Jacksonville Bus Station | Fastest |
Last refresh of the prices: Today at 4:58 AM CST.
Get from Panama City to Jacksonville
The journey takes about 6 hours 45 minutes, and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Jacksonville?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Based on 87402 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $68
Frequently asked questions about travelling from Panama City, US to Jacksonville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Jacksonville?
The cheapest bus tickets from Panama City to Jacksonville start from $68. The average price for this route is around $88. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Jacksonville?
The average bus travel time from Panama City to Jacksonville is 6h 45m, covering a distance of 394 km. The quickest bus can get you there in 6h 45m and is operated by Greyhound.
Which bus companies service the Panama City to Jacksonville route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Panama City to Jacksonville?
The earliest bus departs from Panama City to Jacksonville at 7:25am. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from Panama City to Jacksonville?
A bus trip from Panama City to Jacksonville generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Jacksonville, FL was searched and found on Nov 28, 2025 with a price of $95To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Jacksonville, FL, as early as possible.
You can expect to pay from $95 to $187 for a bus ticket from Panama City, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $95 which is on 2025-11-28.
