Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Diridon Station | CheapestFastest |
Last refresh of the prices: Last Tuesday at 7:26 AM CST.
Get from Panama City to San Jose
The journey takes about 2 days, 9 hours 45 minutes, and with fares starting at just $225, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and San Jose?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in San Jose
- A65 Cahill St., San Jose, CA 95110
- B440 S King rd , an Jose CA 95116
- C
1118 E William St
1118 E William St, San Jose, CA 95116, USA - D
San Jose Bus Stop
100 W San Carlos St, San Jose, CA 95113, USA - E
Tamien Station
Guadalupe Fwy, San Jose, CA 95110, USA - F
Diridon Station
65 Cahill St, San Jose, CA 95110, USA
Compare bus companies
Based on 87402 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $225
Frequently asked questions about travelling from Panama City, US to San Jose, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to San Jose?
The cheapest bus tickets from Panama City to San Jose start from $225. The average price for this route is around $363. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to San Jose?
The average bus travel time from Panama City to San Jose is 2d 9h, covering a distance of 3412 km. The quickest bus can get you there in 2d 8h and is operated by Greyhound.
Which bus companies service the Panama City to San Jose route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Panama City to San Jose?
The earliest bus departs from Panama City to San Jose at 12:50pm. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Panama City to San Jose?
A bus trip from Panama City to San Jose generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to San Jose, US was searched and found on Dec 1, 2025 with a price of $337To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.
You can expect to pay from $337 to $979 for a bus ticket from Panama City, US to San Jose, US based on the last 2 days. You can expect to find the cheapest price for the trip at $337 which is on 2025-12-01.
Top travelled bus routes
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