Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Diridon Station | CheapestFastest |
Last refresh of the prices: Today at 4:38 AM CST.
Get from Panama City to San Jose
The journey takes about 2 days, 9 hours 45 minutes and with fares starting at just $183, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and San Jose?
Stops in San Jose
- A65 Cahill St., San Jose, CA 95110
- B440 S King rd , an Jose CA 95116
- C
1118 E William St
1118 E William St, San Jose, CA 95116, USA - D
San Jose Bus Stop
100 W San Carlos St, San Jose, CA 95113, USA - E
Tamien Station
Guadalupe Fwy, San Jose, CA 95110, USA - F
Diridon Station
65 Cahill St, San Jose, CA 95110, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Panama City, US to San Jose, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to San Jose?
The cheapest bus tickets from Panama City to San Jose start from $183. The average price for this route is around $323. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to San Jose?
The average bus trip duration from Panama City to San Jose is 2d 9h, covering a distance of 2115 miles (3412 km). The quickest bus can get you there in 2d 9h and is operated by Greyhound.
Which bus companies service the Panama City to San Jose route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Panama City to San Jose?
The earliest bus departs from Panama City to San Jose at 2:15pm. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Panama City to San Jose?
A bus trip from Panama City to San Jose generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to San Jose, US was searched and found on Jan 12, 2026 with a price of $225To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.
You can expect to pay from $225 to $643 for a bus ticket from Panama City, US to San Jose, US based on the last 2 days. You can expect to find the cheapest price for the trip at $225 which is on 2026-01-12.
Top traveled bus routes
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Popular bus departures from Panama City
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