What is the travel distance from Panama City to San Jose?

Panama City and San Jose are 2124 miles (3425 km) apart.

What are the departure and arrival stations when taking the bus from Panama City to San Jose?

The majority of buses traveling from Panama City to San Jose start their journey at Panama City Greyhound Bus Station and wind up at Diridon Station. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in San Jose?

Once in San Jose, you can start exploring the city and discover its surroundings. The top sights and things to do are The Tech Museum of Innovation, San Jose Institute of Contemporary Art, San Jose Earthquakes Soccer, Cinnabar Hills Golf Club and Cathedral Basilica of Saint Joseph.

Bus Panama City to San Jose from $126 | Refundable Tickets

Previously seen trips

Next departures for Panama City to San Jose on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:30pm	Panama City Beach Station	2d 11h	5:25am	Diridon Station	No tags
FlixBus + Greyhound	Bus	1:55pm	Panama City Beach Station	2d 18h	6:25am	Diridon Station	No tags
Greyhound + FlixBus	Bus	1:55pm	Panama City Beach Station	2d 17h	5:25am	Diridon Station	No tags
FlixBus + Greyhound	Bus	1:55pm	Panama City Beach Station	2d 17h	5:25am	Diridon Station	No tags
	Bus	12:50pm	Panama City Beach Station	2d 18h	5:25am	Diridon Station	No tags

Get from Panama City to San Jose

This route is served by bus only

The journey takes about 2 days, 9 hours 45 minutes and with fares starting at just $149, it presents an excellent value for a comfortable ride.

1bus per day

2d 9hAverage Duration

2115 milesDistance

85kgCO₂ emissions

Where are the popular stops in Panama City and San Jose?

Stops in Panama City

A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401

Stops in San Jose

A
Diridon Station
65 Cahill St., San Jose, CA 95110
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B
Santiago Express San Jose
440 S King rd , an Jose CA 95116
Visit page
C
1118 E William St
1118 E William St, San Jose, CA 95116, USA
D
San Jose Bus Stop
100 W San Carlos St, San Jose, CA 95113, USA
E
Tamien Station
Guadalupe Fwy, San Jose, CA 95110, USA
F
Diridon Station
65 Cahill St, San Jose, CA 95110, USA

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Panama City, US to San Jose, US by bus

What is the travel distance from Panama City to San Jose?
What are the departure and arrival stations when taking the bus from Panama City to San Jose?
What are the best sights and things to do in San Jose?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

No data

11/23

$664

Today

$657

11/25

No data

11/26

No data

11/27

$363

11/28

No data

11/29

No data

The cheapest trip from Panama City, US to San Jose, US was searched and found on Nov 27, 2025 with a price of $363

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.

You can expect to pay from $363 to $664 for a bus ticket from Panama City, US to San Jose, US based on the last 2 days. You can expect to find the cheapest price for the trip at $363 which is on 2025-11-27.