Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Tampa Bus Station | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound | Bus | Tampa Bus Station | Panama City Beach Station | No tags | ||||
 | Bus | Tampa Bus Station | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound | Bus | University of South Florida | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound | Bus | Tampa Bus Station | Panama City Beach Station | No tags |
Get from Tampa to Panama City
The journey takes about 16 hours 5 minutes and with fares starting at just $53, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tampa and Panama City?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Compare bus companies
Frequently asked questions about traveling from Tampa to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tampa to Panama City?
The cheapest bus tickets from Tampa to Panama City start from $53. The average price for this route is around $81. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tampa to Panama City?
The average bus trip duration from Tampa to Panama City is 16h 5m, covering a distance of 253 miles (407 km). The quickest bus can get you there in 8h 30m and is operated by Greyhound.
Which bus companies service the Tampa to Panama City route?
What is the earliest and latest departure time for the bus from Tampa to Panama City?
The earliest bus departs from Tampa to Panama City at 6:10am. And the latest bus departs at 10:35pm.
What are the CO₂ emissions for the bus trip from Tampa to Panama City?
A bus trip from Tampa to Panama City generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Tampa to Panama City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Tampa to Panama City?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Tampa to Panama City?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Tampa to Panama City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Panama City, US was searched and found on Nov 28, 2025 with a price of $67To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Panama City, US, as early as possible.
You can expect to pay from $67 to $122 for a bus ticket from Tampa to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-11-28.
