Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Tampa Bus Station | Panama City Beach Station | Cheapest | ||||
 | Bus | Tampa Bus Station | Panama City Beach Station | Fastest | ||||
| Bus | Tampa Bus Station | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | University of South Florida | Panama City Beach Station | No tags |
Last refresh of the prices: Yesterday at 8:35 AM EST.
Get from Tampa to Panama City
The journey takes about 11 hours 25 minutes, and with fares starting at just $61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tampa and Panama City?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
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Frequently asked questions about travelling from Tampa to Panama City, US by bus
What is the travel distance from Tampa to Panama City?
The distance between Tampa and Panama City is approximately 398 km (247 miles).
What are the departure and arrival locations for buses traveling from Tampa to Panama City?
Buses departing from Tampa 13th Avenue Bus Stop (McDonald's) in Tampa will take you to Panama City Greyhound Bus Station in Panama City.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Panama City, US was searched and found on Nov 28, 2025 with a price of $97To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Panama City, US, as early as possible.
You can expect to pay from $97 to $139 for a bus ticket from Tampa to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-11-28.
