How much is the bus ticket from San Jose to Panama City?

The cheapest bus tickets from San Jose to Panama City start from $140. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Jose to Panama City?

The average bus trip duration from San Jose to Panama City is 2d 20h, covering a distance of 2115 miles (3412 km). The quickest bus can get you there in 2d 18h and is operated by Greyhound .

Which bus companies service the San Jose to Panama City route?

Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from San Jose to Panama City?

The earliest bus departs from San Jose to Panama City at 12:55am. And the latest bus departs at 11:10pm.

What are the CO₂ emissions for the bus trip from San Jose to Panama City?

A bus trip from San Jose to Panama City generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from San Jose to Panama City?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from San Jose to Panama City?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from San Jose to Panama City?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Jose to Panama City?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus San Jose to Panama City from $166 | Refundable Tickets

Previously seen trips

Next departures for San Jose to Panama City on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	6:10am	Diridon Station	3d 5h	1:40pm	Panama City Beach Station	No tags
FlixBus + Greyhound	Bus	9:10am	Diridon Station	3d 1h	12:35pm	Panama City Beach Station	No tags
Greyhound + FlixBus	Bus	9:10am	Diridon Station	3d 1h	12:35pm	Panama City Beach Station	No tags
FlixBus + Greyhound	Bus	6:30am	Diridon Station	3d 5h	1:40pm	Panama City Beach Station	No tags
Greyhound + FlixBus	Bus	11:10pm	Diridon Station	3d 10h	12:35pm	Panama City Beach Station	No tags

Get from San Jose to Panama City

This route is served by bus only

The journey takes about 2 days, 20 hours and with fares starting at just $140, it presents an excellent value for a comfortable ride.

2bus per day

2d 20hAverage Duration

2115 milesDistance

85kgCO₂ emissions

Where are the popular stops in San Jose and Panama City?

Stops in San Jose

A
Diridon Station
65 Cahill St., San Jose, CA 95110
Visit page
B
Santiago Express San Jose
440 S King rd , an Jose CA 95116
Visit page
C
1118 E William St
1118 E William St, San Jose, CA 95116, USA
D
San Jose Bus Stop
100 W San Carlos St, San Jose, CA 95113, USA
E
Tamien Station
Guadalupe Fwy, San Jose, CA 95110, USA
F
Diridon Station
65 Cahill St, San Jose, CA 95110, USA

Stops in Panama City

A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401

Compare bus companies

Greyhound

3.5/587,407 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,472 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from San Jose, US to Panama City, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Jose to Panama City?
The cheapest bus tickets from San Jose to Panama City start from $140. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Jose to Panama City?
The average bus trip duration from San Jose to Panama City is 2d 20h, covering a distance of 2115 miles (3412 km). The quickest bus can get you there in 2d 18h and is operated by Greyhound.
Which bus companies service the San Jose to Panama City route?
Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from San Jose to Panama City?
The earliest bus departs from San Jose to Panama City at 12:55am. And the latest bus departs at 11:10pm.
What are the CO₂ emissions for the bus trip from San Jose to Panama City?
A bus trip from San Jose to Panama City generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Jose to Panama City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from San Jose to Panama City?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from San Jose to Panama City?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Jose to Panama City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/26

No data

11/27

No data

Today

No data

11/29

$585

11/30

No data

12/01

No data

12/02

No data

12/03

$241

The cheapest trip from San Jose, US to Panama City, US was searched and found on Dec 3, 2025 with a price of $241

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Jose, US to Panama City, US, as early as possible.

You can expect to pay from $241 to $585 for a bus ticket from San Jose, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $241 which is on 2025-12-03.