Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Heading North go to North-bound side of building., Heading South go to South-bound side of building., Mile Marker 94 Florida's Turnpike, West Palm Beach, FL 33413, USATurnpike MM94
C - Okeechobee Rd & I-95
Shell Station , 1850 Okeechobee Blvd, West Palm Beach, FL 33409, USA
D - Lake Worth Service Plaza
8195 Lake Worth Rd, Lake Worth FL 33467 USA, FLORIDAS TURNPIKE MILE 94
E - Vedado
El Barrio Grocery, 3905 Lake Ave, West Palm Beach, FL 33405, USA
Frequently asked questions about traveling from Key West to West Palm Beach by bus
What is the distance between Key West and West Palm Beach?
About 184 miles (297 km) separate Key West and West Palm Beach.
What are the departure and arrival stations when taking the bus from Key West to West Palm Beach?
If you're headed to West Palm Beach from Key West, chances are that your bus will leave from Caroline St and arrive at Tri-Rail & Greyhound. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in West Palm Beach?
Once in West Palm Beach, you can start exploring the city and discover its surroundings. The top sights and things to do are Skydive Palm Beach, Jim Abernethy's SCUBA Adventures Inc, Apoxee Trail, West Palm Beach Airboat Rides and Mounts Botanical Garden.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$45
11/18
$44
Today
$54
11/20
$40
11/21
$34
11/22
$35
11/23
No data
11/24
No data
The cheapest trip from Key West to West Palm Beach was searched and found on Nov 21, 2025 with a price of $34
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key West to West Palm Beach, as early as possible.
You can expect to pay from $34 to $54 for a bus ticket from Key West to West Palm Beach based on the last 2 days. You can expect to find the cheapest price for the trip at $34 which is on 2025-11-21.
The cheapest trip from Key West to West Palm Beach was searched and found on Nov 21, 2025 with a price of $34
