How far is Iowa City from St. Louis?

The distance covered from Iowa City to St. Louis is 357 km (221 miles).

What are the departure and arrival locations for buses traveling from Iowa City to St. Louis?

Buses traveling this route start their trip at Court Street Bus Station, in Iowa City, and end it at Gateway Station, in St. Louis.

Bus Iowa City to St. Louis from $130 | Refundable Tickets

Next bus departures

Next departures for Iowa City to St. Louis on November 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:50am	Iowa City	15h 35m	11:25pm	Gateway Station	CheapestFastest
	Bus	11:50am	Iowa City	18h 35m	6:25am	Gateway Station	No tags

Last refresh of the prices: Yesterday at 11:22 PM CST.

Get from Iowa City to St. Louis

This route is served by bus only

The journey takes about 15 hours 35 minutes, and with fares starting at just $144, it presents an excellent value for a comfortable ride.

2bus per day

15h 35mAverage Duration

356 kmDistance

9kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,367 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

Wifi5

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Iowa City and St. Louis?

Stops in Iowa City

A - Court Street Bus Station

Stops in St. Louis

A - Gateway Station

Frequently asked questions about travelling from Iowa City to St. Louis by bus

How far is Iowa City from St. Louis?
The distance covered from Iowa City to St. Louis is 357 km (221 miles).
What are the departure and arrival locations for buses traveling from Iowa City to St. Louis?
Buses traveling this route start their trip at Court Street Bus Station, in Iowa City, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-09

No data

11-10

No data

Today

No data

11-12

$130

11-13

No data

11-14

No data

11-15

No data

11-16

No data

The cheapest trip from Iowa City to St. Louis was searched and found on Nov 12, 2025 with a price of $130

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iowa City to St. Louis, as early as possible.

You can expect to pay from $130 to $130 for a bus ticket from Iowa City to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $130 which is on 2025-11-12.