What is the distance between St. Louis and Buffalo?

St. Louis and Buffalo are 1065 km (660 miles) apart.

What are the departure and arrival locations for buses traveling from St. Louis to Buffalo?

Buses departing from Gateway Station in St. Louis will take you to Buffalo Airport in Buffalo.

Bus St. Louis to Buffalo from $137 | Refundable Tickets

Previously seen trips

Next departures for St. Louis to Buffalo on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	1:45pm	Gateway Station	1d 1h	4:15pm	Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States)	No tags
Greyhound + FlixBus	Bus	12:50am	Gateway Station	1d 14h	4:10pm	Buffalo (BUF) Airport	No tags
Greyhound + FlixBus	Bus	1:30pm	Gateway Station	1d 7h	10:25pm	Buffalo (BUF) Airport	No tags
	Bus	1:45pm	Gateway Station	1d 1h	4:15pm	Niagara Frontier Transportation Authority	No tags
	Bus	1:55pm	Gateway Station	1d 1h	4:15pm	Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States)	No tags

Compare 2 ways to go from St. Louis to Buffalo

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 8 hours 45 minutes, and with fares starting at just $181, it presents an excellent value for a comfortable ride.

2bus per day

1d 8hAverage Duration

1077 kmDistance

27kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$181 - $365	Average Duration1d 8h	CO₂ emissions 27kg CO₂e
Train	Average Price$206 - $1,384	Average Duration16h 58m	CO₂ emissions 98kg CO₂e

Where are the popular stops in St. Louis and Buffalo?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
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Stops in Buffalo

A
Buffalo Airport
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B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
Visit page
C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
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Compare bus companies

Greyhound

3.5/587,397 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87397 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $181

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from St. Louis to Buffalo, NY by bus

What is the distance between St. Louis and Buffalo?
St. Louis and Buffalo are 1065 km (660 miles) apart.
What are the departure and arrival locations for buses traveling from St. Louis to Buffalo?
Buses departing from Gateway Station in St. Louis will take you to Buffalo Airport in Buffalo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-24

No data

11-25

$193

Today

No data

11-27

No data

11-28

$223

11-29

No data

11-30

No data

12-01

No data

The cheapest trip from St. Louis to Buffalo, NY was searched and found on Nov 25, 2025 with a price of $193

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Buffalo, NY, as early as possible.

You can expect to pay from $193 to $223 for a bus ticket from St. Louis to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $223 which is on 2025-11-28.