Find coaches from St. Louis to Buffalo, NY

Previously seen journeys

Next departures from St. Louis to Buffalo on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Gateway Station
    		Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States)No tags
    Greyhound + FlixBus
      		Gateway Station
      		Buffalo (BUF) AirportNo tags
      FlixBus + Greyhound
        		Gateway Station
        		Buffalo (BUF) AirportNo tags
        Greyhound
          		Gateway Station
          		Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States)No tags
          Greyhound + FlixBus
            		Gateway Station
            		Buffalo (BUF) AirportNo tags

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Compare 2 ways to travel from St. Louis to Buffalo

            We recommend taking the train

            Among the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 16 hours 58 minutes and with fares starting at just US$126, it presents an excellent value for a comfortable ride.

            2train per day
            16h 58mAverage duration
            1077 kmDistance
            98kgCO₂ emissions
            Bus
            		Average priceUS$75 - US$241Average duration1d 8h
            27kg CO₂e
            Train
            		Average priceUS$126 - US$671Average duration16h 58m
            98kg CO₂e

            Bus St. Louis to Buffalo, NY: Trip Overview

            Average ticket priceUS$113
            Average bus trip duration1d 8h
            Number of daily buses2
            Earliest bus departure08:45
            Distance1064 km
            Latest bus departure13:55

            St. Louis to Buffalo Bus

            Busbud helps you find a bus from St. Louis to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            We make sure you can find a bus service from St. Louis to Buffalo from the most reliable bus companies operating this trip.

            From cheap bus tickets to more luxurious buses travelling from St. Louis to Buffalo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip St. Louis - Buffalo, NY

            1. How much does a bus ticket from St. Louis to Buffalo cost?

              The bus ticket price from St. Louis to Buffalo starts at US$75. The best way to find cheap bus tickets from St. Louis to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from St. Louis to Buffalo?

              The average travel time between St. Louis and Buffalo is around 1d 8h, although the fastest bus will take about 1d 1h. This is the time it takes to travel the 1065 km that separates the two cities.

            3. How many daily bus connections are there between St. Louis and Buffalo?

              The number of buses from St. Louis to Buffalo can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from St. Louis to Buffalo by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from St. Louis to Buffalo?

              When taking the bus from St. Louis to Buffalo, you can travel comfortably and safely with Greyhound.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            No data
            01/11
            No data
            Today
            No data
            03/11
            US$68
            04/11
            No data
            05/11
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            06/11
            No data
            07/11
            No data
            busbud logoThe cheapest trip from St. Louis to Buffalo, NY was searched and found on 03 Nov 2025 with a price of US$68

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Buffalo, NY as early as possible.

            You can expect to pay from US$68 to US$68 for a bus ticket from St. Louis to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at US$68, which is on 2025-11-03.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St. Louis and Buffalo!

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to Buffalo, get comfy and count the stars.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Buffalo that are otherwise impossible to come by with a plane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Louis to Buffalo.

            Did you know?

            Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            What's the cheapest way to go from St. Louis to Buffalo, NY?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to St. Louis by bus?

            Bus from Buffalo, NY to St. Louis

            You can also go to Buffalo, NY by train

            Train from St. Louis to Buffalo, NY

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

            People from around the world trust Busbud

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