What is the travel distance from Buffalo to St. Louis?

It's about 1065 km (660 miles) from Buffalo to St. Louis.

What are the departure and arrival locations for buses traveling from Buffalo to St. Louis?

Buses departing from Buffalo Airport in Buffalo will take you to Gateway Station in St. Louis.

Bus Buffalo to St. Louis from $163 | Refundable Tickets

Previously seen trips

Next departures for Buffalo to St. Louis on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	7:50pm	Niagara Frontier Transportation Authority	1d 4h	11:15pm	Gateway Station	No tags
FlixBus + Greyhound	Bus	11:20pm	Buffalo (BUF) Airport	1d 16h	3:10pm	Gateway Station	No tags
Greyhound + FlixBus	Bus	11:20pm	Buffalo (BUF) Airport	1d 16h	3:10pm	Gateway Station	No tags
FlixBus + Greyhound	Bus	7:50pm	Niagara Frontier Transportation Authority	1d 4h	11:35pm	Gateway Station	No tags
FlixBus + Greyhound	Bus	11:20pm	Buffalo (BUF) Airport	1d 16h	3:20pm	Gateway Station	No tags

Compare 2 ways to go from Buffalo to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 20 hours 28 minutes, and with fares starting at just $279, it presents an excellent value for a comfortable ride.

1train per day

20h 28mAverage Duration

1077 kmDistance

98kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$161 - $506	Average Duration1d 10h	CO₂ emissions 27kg CO₂e
Train	Average Price$279 - $1,507	Average Duration20h 28m	CO₂ emissions 98kg CO₂e

Where are the popular stops in Buffalo and St. Louis?

Stops in Buffalo

A
Buffalo Airport
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B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
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C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
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Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87394 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $184

Greyhound Buffalo St. Louis recent customer reviews

If there is any delayed customers should be notified and updated as soon as possible

Marta G.

January 3, 2020

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Buffalo, NY to St. Louis by bus

What is the travel distance from Buffalo to St. Louis?
It's about 1065 km (660 miles) from Buffalo to St. Louis.
What are the departure and arrival locations for buses traveling from Buffalo to St. Louis?
Buses departing from Buffalo Airport in Buffalo will take you to Gateway Station in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-23

$167

11-24

No data

Today

$163

11-26

$220

11-27

No data

11-28

No data

11-29

No data

11-30

$495

The cheapest trip from Buffalo, NY to St. Louis was searched and found on Nov 25, 2025 with a price of $163

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to St. Louis, as early as possible.

You can expect to pay from $163 to $495 for a bus ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $220 which is on 2025-11-26.