How far is St. Louis from Buffalo by coach?

The journey from Buffalo to St. Louis by coach covers an approximate distance of 660 miles (1065 km).

Is there a way to reach St. Louis from Buffalo without flying?

You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Bus Buffalo to St. Louis from £87 | Refundable Tickets

Previously seen journeys

Next departures from Buffalo to St. Louis on 25 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	19:50	Niagara Frontier Transportation Authority	1d 4h	23:15	Gateway Station	No tags
FlixBus + Greyhound	Bus	23:20	Buffalo (BUF) Airport	1d 16h	15:10	Gateway Station	No tags
Greyhound + FlixBus	Bus	23:20	Buffalo (BUF) Airport	1d 16h	15:10	Gateway Station	No tags
FlixBus + Greyhound	Bus	19:50	Niagara Frontier Transportation Authority	1d 4h	23:35	Gateway Station	No tags
FlixBus + Greyhound	Bus	23:20	Buffalo (BUF) Airport	1d 16h	15:20	Gateway Station	No tags

Compare 2 ways to travel from Buffalo to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 20 hours 28 minutes and with fares starting at just £150, it presents an excellent value for a comfortable ride.

1train per day

20h 28mAverage duration

668 milesDistance

98kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£86 - £271	Average duration1d 10h	CO₂ emissions 27kg CO₂e
Train	Average price£150 - £808	Average duration20h 28m	CO₂ emissions 98kg CO₂e

Where are the popular stops in Buffalo and St. Louis?

Stops in Buffalo

A
Buffalo Airport
Visit page
B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
Visit page
C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87394 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £99

Greyhound Buffalo St. Louis recent customer reviews

If there is any delayed customers should be notified and updated as soon as possible

Marta G.

3 January 2020

FlixBus

3.5/511,443 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling by bus from Buffalo, NY to St. Louis

How far is St. Louis from Buffalo by coach?
The journey from Buffalo to St. Louis by coach covers an approximate distance of 660 miles (1065 km).
Is there a way to reach St. Louis from Buffalo without flying?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

23/11

£90

24/11

No data

Today

£87

26/11

£118

27/11

No data

28/11

No data

29/11

No data

30/11

£266

The cheapest trip from Buffalo, NY to St. Louis was searched and found on 25 Nov 2025 with a price of £87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to St. Louis as early as possible.

You can expect to pay from £87 to £266 for a bus ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £118, which is on 2025-11-26.