How far is St. Louis from Indianapolis by coach?

The journey from Indianapolis to St. Louis by coach covers an approximate distance of 230 miles (371 km).

What is the best way to go from Indianapolis to St. Louis without a car?

You can reach St. Louis from Indianapolis by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Bus Indianapolis to St. Louis from £26 | Refundable Tickets

Next departures

Next departures from Indianapolis to St. Louis on 24 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	CheapestFastest

Next departures from Indianapolis to St. Louis on 25 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 26 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	Cheapest
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	Fastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 27 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 28 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 29 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Last refresh of the prices: Yesterday at 13:06 EST.

Compare 2 ways to travel from Indianapolis to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 4 hours 20 minutes and with fares starting at just £31, it presents an excellent value for a comfortable ride.

2bus per day

4h 20mAverage duration

230 milesDistance

9kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£31 - £92	Average duration4h 20m	CO₂ emissions 9kg CO₂e
Train	Average price£51 - £357	Average duration17h 23m	CO₂ emissions 34kg CO₂e

Where are the popular stops in Indianapolis and St. Louis?

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £31

Greyhound Indianapolis St. Louis recent customer reviews

The bus had some problems. Air conditioning was malfunctioning, and none of the outlets worked. There was also considerable damage to the seats that should have been repaired. The counter clerk was very friendly and helpful, but the bus driver seemed to be in a very bad mood and possibly ill, loudly coughing up phlegm the entire trip, and he gave us no indication of how late the bus was going to arrive. I will not ride Greyhound again if I can possibly avoid it.

Tremain X.

25 September 2019

The 3:15 bus never arrived so I was forced to wait 6 hours at the station for the next departure. This was very poorly communicated to passengers and no effort was made for any sort of reimbursement. I will absolutely never use Greyhound again.

Matthew N.

16 August 2018

Amtrak

4/55,606 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

WiFi3.6

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

WiFi5

FlixBus

3.5/511,432 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling by bus from Indianapolis to St. Louis

How far is St. Louis from Indianapolis by coach?
The journey from Indianapolis to St. Louis by coach covers an approximate distance of 230 miles (371 km).
What is the best way to go from Indianapolis to St. Louis without a car?
You can reach St. Louis from Indianapolis by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

22/11

£47

23/11

£101

Today

£49

25/11

£54

26/11

£54

27/11

£46

28/11

£44

29/11

£44

The cheapest trip from Indianapolis to St. Louis was searched and found on 28 Nov 2025 with a price of £44

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to St. Louis as early as possible.

You can expect to pay from £44 to £135 for a bus ticket from Indianapolis to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £44, which is on 2025-11-28.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.