How far is St. Louis from Indianapolis?

The distance between St. Louis and Indianapolis is around 371 km (230 miles).

What are the departure and arrival locations for buses traveling from St. Louis to Indianapolis?

Buses traveling this route start their trip at Gateway Station, in St. Louis, and end it at Greyhound Amtrak Station, in Indianapolis.

Bus St. Louis to Indianapolis from $47 | Refundable Tickets

Next bus departures

Next departures for St. Louis to Indianapolis on November 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	CheapestFastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on November 22
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	Cheapest
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	Fastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	CheapestFastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on November 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	CheapestFastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on November 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	CheapestFastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	CheapestFastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Last refresh of the prices: Yesterday at 11:10 AM CST.

Compare 2 ways to go from St. Louis to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 4 hours 25 minutes, and with fares starting at just $57, it presents an excellent value for a comfortable ride.

3bus per day

4h 25mAverage Duration

371 kmDistance

9kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$57 - $211	Average Duration4h 25m	CO₂ emissions 9kg CO₂e
Train	Average Price$101 - $861	Average Duration14h 39m	CO₂ emissions 34kg CO₂e

Compare bus companies

Greyhound

3.5/587,382 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87382 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $57

Greyhound St. Louis Indianapolis recent customer reviews

My Journey to Indianapolis was quite interesting. I really like the bus driver he was very approachable. I appreciate that he got us to our destination in Indianapolis safely and early. I must say the bus was a old and I had to change seats several times due to water leaking on top of my head. Otherwise, I had no additional problems but that the bus needed to be upgraded. Please let the bus driver know that he was great and thank him for the chat. Sincerely, Courtney

Courtney M.

October 22, 2019

I hope my round trip back home is better. My bus left 5 1/2 hours later than expected on the ride over to Indianapolis. Plus there were mo clear directions to the busport in St Louis. Even the terminal crew could not tell us where to catch the bus. The address given may have been the address in general for the whole airport. Signage unclear and we drove in circles looking for a busport which was actually across the hwy from the airport.

Linda T.

September 8, 2019

I was under the impression that we would get to our destination around 7:30 but didn’t make it until around 9. I understand there was a time change but I feel like the ticket should have reflected that time change if that was the case.

Tresden M.

October 20, 2018

FlixBus

3.5/511,380 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in St. Louis and Indianapolis?

Stops in St. Louis

A - Gateway Station

Stops in Indianapolis

A - Greyhound Amtrak Station

Frequently asked questions about travelling from St. Louis to Indianapolis by bus

How far is St. Louis from Indianapolis?
The distance between St. Louis and Indianapolis is around 371 km (230 miles).
What are the departure and arrival locations for buses traveling from St. Louis to Indianapolis?
Buses traveling this route start their trip at Gateway Station, in St. Louis, and end it at Greyhound Amtrak Station, in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-17

$90

11-18

$84

Today

$98

11-20

$101

11-21

$84

11-22

$80

11-23

$74

11-24

$84

The cheapest trip from St. Louis to Indianapolis was searched and found on Nov 23, 2025 with a price of $74

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Indianapolis, as early as possible.

You can expect to pay from $74 to $185 for a bus ticket from St. Louis to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-11-23.