Next departures from St. Louis to Indianapolis on 22 November
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Vehicle type
Departure time
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Recommended
Price and booking link
Bus
Gateway Station
Indianapolis Bus Station
CheapestFastest
Bus
Gateway Station
Indianapolis Bus Station
No tags
Bus
Gateway Station
Indianapolis Bus Station
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Next departures from St. Louis to Indianapolis on 23 November
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Vehicle type
Departure time
Departure location
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Recommended
Price and booking link
Bus
Gateway Station
Indianapolis Bus Station
CheapestFastest
Bus
Gateway Station
Indianapolis Bus Station
No tags
Bus
Gateway Station
Indianapolis Bus Station
No tags
Next departures from St. Louis to Indianapolis on 24 November
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Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Indianapolis Bus Station
CheapestFastest
Bus
Gateway Station
Indianapolis Bus Station
No tags
Bus
Gateway Station
Indianapolis Bus Station
No tags
Next departures from St. Louis to Indianapolis on 25 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Indianapolis Bus Station
CheapestFastest
Bus
Gateway Station
Indianapolis Bus Station
No tags
Bus
Gateway Station
Indianapolis Bus Station
No tags
Next departures from St. Louis to Indianapolis on 26 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Indianapolis Bus Station
Cheapest
Bus
Gateway Station
Indianapolis Bus Station
Fastest
Bus
Gateway Station
Indianapolis Bus Station
No tags
Last refresh of the prices: Today at 07:58 CST.
Compare 2 ways to travel from St. Louis to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 4 hours 25 minutes and with fares starting at just £31, it presents an excellent value for a comfortable ride.
Based on 87386 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £31
Greyhound St. Louis Indianapolis recent customer reviews
My Journey to Indianapolis was quite interesting. I really like the bus driver he was very approachable.
I appreciate that he got us to our destination in Indianapolis safely and early. I must say the bus was a old and I had to change seats several times due to water leaking on top of my head. Otherwise, I had no additional problems but that the bus needed to be upgraded.
Please let the bus driver know that he was great and thank him for the chat.
Sincerely,
Courtney
5 out of 5 stars
Courtney M.
I hope my round trip back home is better. My bus left 5 1/2 hours later than expected on the ride over to Indianapolis. Plus there were mo clear directions to the busport in St Louis. Even the terminal crew could not tell us where to catch the bus. The address given may have been the address in general for the whole airport. Signage unclear and we drove in circles looking for a busport which was actually across the hwy from the airport.
2 out of 5 stars
Linda T.
I was under the impression that we would get to our destination around 7:30 but didn’t make it until around 9. I understand there was a time change but I feel like the ticket should have reflected that time change if that was the case.
Based on 11388 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £92
Frequently asked questions about travelling by bus from St. Louis to Indianapolis
What's the distance between St. Louis and Indianapolis by coach?
The distance between St. Louis and Indianapolis by coach is approximately 230 miles (371 km).
How can I get from St. Louis to Indianapolis without driving?
The best way to go from St. Louis to Indianapolis without a car is by coach. They are frequent and reliable, offering a convenient and eco-friendly journey. Depending on your preferences, carpooling can also be considered as an option.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
18/11
£46
19/11
£54
Today
£55
21/11
£58
22/11
£51
23/11
£40
24/11
£46
25/11
£46
The cheapest trip from St. Louis to Indianapolis was searched and found on 23 Nov 2025 with a price of £40
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Indianapolis as early as possible.
You can expect to pay from £40 to £101 for a bus ticket from St. Louis to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at £40, which is on 2025-11-23.
What's the cheapest way to go from St. Louis to Indianapolis?
The bus is the cheapest travel choice for this destination
The cheapest trip from St. Louis to Indianapolis was searched and found on 23 Nov 2025 with a price of £40
The bus is the cheapest travel choice for this destination
