Next bus departures Today, Nov 27 Tomorrow, Nov 28 Sat, Nov 29 Sun, Nov 30 Mon, Dec 1 Tue, Dec 2 Wed, Dec 3 More dates
Next departures for Iowa City to Chicago on November 27 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Greyhound Lines, Inc. + FlixBus
Bus 1:55pm
Iowa City 5h 45m 7:40pm
Chicago 95Th & Dan Ryan Cheapest $87 Bus 1:55pm
Iowa City 4h 20m 6:15pm
Downtown Greyhound Station Fastest $91 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station No tags $155 Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 45m 6:35pm
Chicago 95Th & Dan Ryan No tags $130
Next departures for Iowa City to Chicago on November 28 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 45m 6:35pm
Chicago 95Th & Dan Ryan Cheapest $91 Bus 1:55pm
Iowa City 4h 20m 6:15pm
Downtown Greyhound Station Fastest $97 Bus 7:50am
Iowa City 5h 45m 1:35pm
Downtown Greyhound Station No tags $100 Greyhound Lines, Inc. + FlixBus
Bus 7:50am
Iowa City 9h 15m 5:05pm
Chicago 95Th & Dan Ryan No tags $105 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station No tags $103
Next departures for Iowa City to Chicago on November 29 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 7:50am
Iowa City 5h 45m 1:35pm
Downtown Greyhound Station Cheapest $90 Bus 1:55pm
Iowa City 4h 20m 6:15pm
Downtown Greyhound Station Fastest $91 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station No tags $94 Greyhound Lines, Inc. + FlixBus
Bus 7:50am
Iowa City 9h 15m 5:05pm
Chicago 95Th & Dan Ryan No tags $101 Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 45m 6:35pm
Chicago 95Th & Dan Ryan No tags $101
Next departures for Iowa City to Chicago on November 30 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 7:50am
Iowa City 5h 45m 1:35pm
Downtown Greyhound Station Cheapest $97 Bus 1:55pm
Iowa City 4h 20m 6:15pm
Downtown Greyhound Station Fastest $159 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station No tags $173 Greyhound Lines, Inc. + FlixBus
Bus 7:50am
Iowa City 9h 15m 5:05pm
Chicago 95Th & Dan Ryan No tags $116 Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 30m 6:20pm
Chicago 95Th & Dan Ryan No tags $178
Next departures for Iowa City to Chicago on December 1 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 7:50am
Iowa City 5h 45m 1:35pm
Downtown Greyhound Station Cheapest $68 Bus 1:55pm
Iowa City 4h 20m 6:15pm
Downtown Greyhound Station Fastest $74 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station No tags $120 Greyhound Lines, Inc. + FlixBus
Bus 7:50am
Iowa City 9h 15m 5:05pm
Chicago 95Th & Dan Ryan No tags $107 Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 45m 6:35pm
Chicago 95Th & Dan Ryan No tags $155
Next departures for Iowa City to Chicago on December 2 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 7:50am
Iowa City 5h 45m 1:35pm
Downtown Greyhound Station Cheapest $61 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station Fastest $90 Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 45m 6:35pm
Chicago 95Th & Dan Ryan No tags $97
Next departures for Iowa City to Chicago on December 3 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 7:50am
Iowa City 5h 45m 1:35pm
Downtown Greyhound Station Cheapest $58 Bus 11:50am
Iowa City 5h 25m 5:15pm
Downtown Greyhound Station Fastest $76 Greyhound Lines, Inc. + FlixBus
Bus 11:50am
Iowa City 6h 45m 6:35pm
Chicago 95Th & Dan Ryan No tags $78
Last refresh of the prices: Today at 1:32 AM CST.
View all departures Get from Iowa City to Chicago This route is served by bus only
The journey takes about 5 hours 45 minutes, and with fares starting at just $52, it presents an excellent value for a comfortable ride.
Where are the popular stops in Iowa City and Chicago? Stops in Iowa City A
Court Street Bus Station
170 E Court St, Iowa City, IA 52240, USA Map
Stops in Chicago C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA Map
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA Map
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA Map
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA Map
Compare bus companies 4 out of 5 stars 4/5 20 reviews
Staff 5
Timeliness 5
Cleanliness 5
Wifi 5
Based on 20 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Burlington Trailways ticket prices on this trip start at $141
3.5 out of 5 stars 3.5/5 87,401 reviews
Staff 3.6
Timeliness 2.9
Cleanliness 3.3
Wifi 2.4
Based on 87401 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $58
Frequently asked questions about travelling from Iowa City to Chicago by bus
What is the distance between Iowa City and Chicago? It's about 323 km (201 miles) from Iowa City to Chicago.
What are the departure and arrival locations for buses traveling from Iowa City to Chicago? Buses departing from Court Street Bus Station in Iowa City will take you to Downtown Greyhound Station in Chicago.
Find cheapest prices for buses Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Iowa City to Chicago was searched and found on Dec 2, 2025 with a price of $51 To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iowa City to Chicago, as early as possible.
You can expect to pay from $51 to $163 for a bus ticket from Iowa City to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-12-02.
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Popular bus departures from Iowa City Popular bus routes to Chicago Continue your journey from Chicago 
The cheapest trip from Iowa City to Chicago was searched and found on Dec 2, 2025 with a price of $51
