Bus Tickets from Houston, US to Santa Ana, US

Next departures

Next departures for Houston to Santa Ana on November 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Houston Bus Station
    		Santa Ana Bus StationCheapestFastest
    Greyhound Lines, Inc.
      		Houston Bus Station
      		Anaheim Regional Transportation Intermodal CenterNo tags
      Greyhound Lines, Inc. + FlixBus
        		Houston Bus Station
        		UC Irvine (Crawford Hall)No tags
        FlixBus + Valley Transit + Greyhound Lines, Inc.
          		Downtown Gray & Smith
          		Anaheim Regional Transportation Intermodal CenterNo tags
          Valley Transit + Greyhound Lines, Inc.
            		Hillcroft Ave & Southwest Freeway
            		Anaheim Regional Transportation Intermodal CenterNo tags

            Last refresh of the prices: Yesterday at 8:20 PM CST.

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            Get from Houston to Santa Ana

            This route is served by bus only

            The journey takes about 1 day, 16 hours 35 minutes and with fares starting at just $217, it presents an excellent value for a comfortable ride.

            21bus per day
            1d 16hAverage Duration
            1350 milesDistance
            54kgCO₂ emissions

            Bus Houston, US to Santa Ana, US: Trip Overview

            Average ticket price$256
            Average bus trip duration1d 16h
            Number of daily buses21
            Earliest bus departure2:00am
            Distance1350 miles (2177 km)
            Latest bus departure7:50pm

            Houston to Santa Ana Bus

            Busbud helps you find a bus from Houston to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            Bus service from Houston to Santa Ana will be provided by the most trusted bus companies.

            From cheap bus tickets to more luxurious buses traveling from Houston to Santa Ana, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions for your trip Houston, US - Santa Ana, US

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/03
            No data
            11/04
            No data
            Today
            No data
            11/06
            $231
            11/07
            No data
            11/08
            No data
            11/09
            No data
            11/10
            No data
            busbud logoThe cheapest trip from Houston, US to Santa Ana, US was searched and found on Nov 6, 2025 with a price of $231

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Santa Ana, US, as early as possible.

            You can expect to pay from $231 to $287 for a bus ticket from Houston, US to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at $231 which is on 2025-11-06.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Houston and Santa Ana!

            Much more than a mere vehicle taking you from Houston to Santa Ana, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Houston to Santa Ana that are otherwise impossible to come by with a plane.

            Make a music playlist for your bus ride from Houston to Santa Ana, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            Will you be returning to Houston, US by bus?

            Bus from Santa Ana, US to Houston, US

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