How much is the bus ticket from San Ysidro to Santa Ana?

The cheapest bus tickets from San Ysidro to Santa Ana start from $27. The average price for this route is around $45. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Ysidro to Santa Ana?

The average bus trip duration from San Ysidro to Santa Ana is 2h 45m, covering a distance of 96 miles (155 km). The quickest bus can get you there in 1h 30m and is operated by Los Limousines .

Which bus companies service the San Ysidro to Santa Ana route?

Several major bus companies operate on this route with 17 buses available per day, including services from Los Limousines , FlixBus , Greyhound , Fronteras del Norte .

What is the earliest and latest departure time for the bus from San Ysidro to Santa Ana?

The earliest bus departs from San Ysidro to Santa Ana at 1:00am. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from San Ysidro to Santa Ana?

A bus trip from San Ysidro to Santa Ana generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from San Ysidro to Santa Ana?

According to Busbud customers, the highest-rated bus company on this route is Fronteras del Norte , with an average rating of 3.6 out of 5 stars based on 3 reviews.

Which bus company has the best Wi-Fi from San Ysidro to Santa Ana?

Based on reviews on Busbud, the bus company Los Limousines has the best Wi-Fi rating with a score of 2.8.

Which bus company has the most timely service from San Ysidro to Santa Ana?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Ysidro to Santa Ana?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Fronteras del Norte , with a cleanliness rating of 5.0 out of 5 stars.

Bus San Ysidro to Santa Ana from $20 | Refundable Tickets

Next bus departures

Next departures for San Ysidro to Santa Ana on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:00pm	San Ysidro Bus terminal	2h 35m	9:35pm	Anaheim Regional Transportation Intermodal Center	Cheapest
Bus	3:25pm	San Ysidro Bus terminal	2h 5m	5:30pm	UC Irvine (Crawford Hall)	Fastest
Bus	7:00pm	San Ysidro Bus terminal	2h 20m	9:20pm	Santa Ana Bus Station	No tags
Bus	1:00pm	San Ysidro Greyhound Bus Station	2h 45m	3:45pm	Santa Ana E Santa Ana Blvd	No tags
Bus	1:00pm	San Ysidro Greyhound Bus Station	4h	5:00pm	Santa Ana E Santa Ana Blvd	No tags

Next departures for San Ysidro to Santa Ana on November 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:00am	San Ysidro Bus terminal	2h 40m	8:40am	Santa Ana Bus Station	Cheapest
Bus	10:00am	San Ysidro Greyhound Bus Station	2h	12:00pm	Santa Ana E Santa Ana Blvd	Fastest
Bus	11:25am	San Ysidro Bus terminal	3h 20m	2:45pm	Anaheim Regional Transportation Intermodal Center	No tags
Bus	7:00pm	San Ysidro Bus terminal	2h 35m	9:35pm	Anaheim Regional Transportation Intermodal Center	No tags
Bus	1:15am	San Ysidro Greyhound Bus Station	2h 30m	3:45am	Santa Ana E Santa Ana Blvd	No tags

Last refresh of the prices: Yesterday at 11:16 PM PST.

Get from San Ysidro to Santa Ana

This route is served by bus only

The journey takes about 2 hours 45 minutes and with fares starting at just $27, it presents an excellent value for a comfortable ride.

17bus per day

2h 45mAverage Duration

96 milesDistance

4kgCO₂ emissions

Where are the popular stops in San Ysidro and Santa Ana?

Stops in San Ysidro

A
San Ysidro Greyhound Bus Station
731 E San Ysidro Blvd, San Ysidro, CA 92173
Visit page

Stops in Santa Ana

A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701
B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA

Compare bus companies

Los Limousines

3.5/5272 reviews

Staff4.2

Timeliness2.8

Cleanliness3.9

Wifi2.7

FlixBus

3.5/511,465 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,403 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound San Ysidro Santa Ana recent customer reviews

Bus was two an hour and fifty minute late, and there was a foul smell from the sewage in the bathroom

Tlaloc C.

July 11, 2023

Excellent service and excellent value...same as earlier trip from Los Angeles to san Ysidro

Michael N.

December 4, 2019

Worst service.

Benjamin S.

August 21, 2018

Fronteras del Norte

3.5/53 reviews

Staff5

Timeliness1.7

Cleanliness5

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from San Ysidro, CA to Santa Ana, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Ysidro to Santa Ana?
The cheapest bus tickets from San Ysidro to Santa Ana start from $27. The average price for this route is around $45. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Ysidro to Santa Ana?
The average bus trip duration from San Ysidro to Santa Ana is 2h 45m, covering a distance of 96 miles (155 km). The quickest bus can get you there in 1h 30m and is operated by Los Limousines.
Which bus companies service the San Ysidro to Santa Ana route?
Several major bus companies operate on this route with 17 buses available per day, including services from Los Limousines, FlixBus, Greyhound, Fronteras del Norte.
What is the earliest and latest departure time for the bus from San Ysidro to Santa Ana?
The earliest bus departs from San Ysidro to Santa Ana at 1:00am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from San Ysidro to Santa Ana?
A bus trip from San Ysidro to Santa Ana generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Ysidro to Santa Ana?
According to Busbud customers, the highest-rated bus company on this route is Fronteras del Norte, with an average rating of 3.6 out of 5 stars based on 3 reviews.
Which bus company has the best Wi-Fi from San Ysidro to Santa Ana?
Based on reviews on Busbud, the bus company Los Limousines has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from San Ysidro to Santa Ana?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Ysidro to Santa Ana?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Fronteras del Norte, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/26

$32

11/27

$30

Today

$29

11/29

No data

11/30

$29

12/01

No data

12/02

No data

12/03

No data

The cheapest trip from San Ysidro, CA to Santa Ana, US was searched and found on Nov 28, 2025 with a price of $29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Santa Ana, US, as early as possible.

You can expect to pay from $29 to $61 for a bus ticket from San Ysidro, CA to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at $29 which is on 2025-11-30.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.