Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Houston Bus Station | 1116 Woodruff Rd | Cheapest | |||||
 | Houston Lockwood, (TX - TBC Lockwood) | Greenville, (SC - Taqueria Guadalajara #3) | Fastest | |||||
| Houston Bus Station | 1116 Woodruff Rd | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Houston Bus Station | 1116 Woodruff Rd | No tags | |||||
Valley Transit + Greyhound Lines, Inc. + FlixBus | Hillcroft Ave & Southwest Freeway | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Today at 8:45 AM CST.
Compare 2 ways to go from Houston to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 3 hours 50 minutes, and with fares starting at just $149, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and Greenville?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling from Houston, US to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to Greenville?
The cheapest bus tickets from Houston to Greenville start from $149. The average price for this route is around $222. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to Greenville?
The average bus travel time from Houston to Greenville is 1d 3h, covering a distance of 1351 km. The quickest bus can get you there in 15h 11m and is operated by Tornado Bus.
Which bus companies service the Houston to Greenville route?
Several major bus companies operate on this route with 21 buses available per day, including services from Greyhound, Tornado Bus, Amtrak, FlixBus, Valley Transit.
What are the earliest and latest departure times for the bus from Houston to Greenville?
The earliest bus departs from Houston to Greenville at 2:00am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to Greenville?
A bus trip from Houston to Greenville generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Houston to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Houston to Greenville?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Houston to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Greenville, SC was searched and found on Dec 4, 2025 with a price of $188To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Greenville, SC, as early as possible.
You can expect to pay from $188 to $2,895 for a bus ticket from Houston, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $188 which is on 2025-12-04.
Usually Amtrak, Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Houston, US to Greenville, SC?
The bus is the cheapest travel choice for this destination
