Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Baytown, 6800 Thompson Rd | 1116 Woodruff Rd | Cheapest | |||||
 | Houston Lockwood, (TX - TBC Lockwood) | Greenville, (SC - Taqueria Guadalajara #3) | Fastest | |||||
 | Amtrak Station | Greenville Station | No tags | |||||
 | Houston Bus Station | 1116 Woodruff Rd | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Houston Bus Station | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Yesterday at 23:27 CST.
Compare 2 ways to travel from Houston to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 3 hours 50 minutes and with fares starting at just £81, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and Greenville?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling by bus from Houston, US to Greenville, SC
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Houston to Greenville?
The cheapest coach tickets from Houston to Greenville start from £81. The average price for this route is around £120. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Houston to Greenville?
The average bus journey time from Houston to Greenville is 1d 3h, covering a distance of 838 miles. The fastest bus can take you there in 15h 11m and is operated by Tornado Bus.
Which bus companies service the Houston to Greenville route?
Several major bus companies operate on this route with 21 buses available per day, including services from Greyhound, Tornado Bus, Amtrak, FlixBus, Valley Transit.
What is the earliest and latest departure time for the bus from Houston to Greenville?
The earliest bus departs from Houston to Greenville at 02:00. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Houston to Greenville?
A bus journey from Houston to Greenville produces an estimated 34 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Houston to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which company has the best Wi-Fi from Houston to Greenville?
Based on Busbud reviews, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Houston to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Greenville, SC was searched and found on 4 Dec 2025 with a price of £101To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Greenville, SC as early as possible.
You can expect to pay from £101 to £1,563 for a bus ticket from Houston, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £101, which is on 2025-12-04.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Houston, US to Greenville, SC?
The bus is the cheapest travel choice for this destination
