Bus from Houston, US to Greenville, SC: Tickets & Schedules
Next departures
Next departures for Houston to Greenville on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
Cheapest
FlixBus + Greyhound Lines, Inc.
Downtown Gray & Smith
1116 Woodruff Rd
Fastest
Amtrak Station
Greenville Station
No tags
Houston Bus Station
1116 Woodruff Rd
No tags
FlixBus + Greyhound Lines, Inc.
Downtown Gray & Smith
1116 Woodruff Rd
No tags
Next departures for Houston to Greenville on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Baytown, 6800 Thompson Rd
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Houston Bus Station
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Hillcroft Ave & Southwest Freeway
1116 Woodruff Rd
No tags
Last refresh of the prices: Yesterday at 5:16 PM CST.
Compare 2 ways to go from Houston to Greenville
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 3 hours 50 minutes and with fares starting at just $104, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,2 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $216 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $446
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 33 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the departure location and the staff but often complained with the wifi. Valley Transit ticket prices on this trip start at $109
Frequently asked questions about traveling from Houston, US to Greenville, SC by bus
What is the travel distance from Houston to Greenville?
About 834 miles (1344 km) separate Houston and Greenville.
What are the departure and arrival stations when taking the bus from Houston to Greenville?
The majority of buses traveling from Houston to Greenville start their journey at Hillcroft Ave & Southwest Freeway and wind up at Guadalajara Supermarket Bus Stop. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$209
11/25
No data
Today
$215
11/27
$193
11/28
$131
11/29
$143
11/30
$150
12/01
$148
The cheapest trip from Houston, US to Greenville, SC was searched and found on Nov 28, 2025 with a price of $131
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Greenville, SC, as early as possible.
You can expect to pay from $131 to $1,794 for a bus ticket from Houston, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $131 which is on 2025-11-28.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Houston, US to Greenville, SC?
The bus is the cheapest travel choice for this destination
The cheapest trip from Houston, US to Greenville, SC was searched and found on Nov 28, 2025 with a price of $131
The bus is the cheapest travel choice for this destination
