Next departures for New York City to Greenville on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
103 Canal St
1111 Woodruff Road
CheapestFastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
103 Canal St
1111 Woodruff Road
CheapestFastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
103 Canal St
1111 Woodruff Road
CheapestFastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
103 Canal St
1111 Woodruff Road
CheapestFastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
103 Canal St
1111 Woodruff Road
CheapestFastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff Rd
Cheapest
Bus
103 Canal St
1111 Woodruff Road
Fastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on December 3
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
New York Port Authority
1116 Woodruff Rd
Cheapest
Bus
103 Canal St
1111 Woodruff Road
Fastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Next departures for New York City to Greenville on December 4
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Chinatown
1116 Woodruff Rd
Cheapest
Bus
103 Canal St
1111 Woodruff Road
Fastest
Bus
103 Canal St
1111 Woodruff Road
No tags
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff Rd
No tags
Last refresh of the prices: Yesterday at 3:05 PM EST.
Compare 2 ways to go from New York City to Greenville
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 15 hours 24 minutes and with fares starting at just $153, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Wanda Coach is one of the main Chinatown bus carriers in the US, connecting about 75 cities around the country with inexpensive tickets and comfortable bus rides. Wanda Coach buses travel between Chinatown neighborhoods with direct buses that are affordable, safe and have convenient pick-up and drop-off locations. If you travel with Wanda Coach, you can reschedule your tickets for a $10 fee up to 2 hours before travel time, and their buses have free WiFi, power outlets and bathrooms.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound New York City Greenville recent customer reviews
Only that about 5 hours is in waiting which makes the trip SO long
Frequently asked questions about traveling from New York City to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from New York City to Greenville?
The cheapest bus tickets from New York City to Greenville start from $80. The average price for this route is around $123. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from New York City to Greenville?
The average bus trip duration from New York City to Greenville is 17h 10m, covering a distance of 615 miles (991 km). The quickest bus can get you there in 13h and is operated by Wanda Coach.
Which bus companies service the New York City to Greenville route?
Several major bus companies operate on this route with 33 buses available per day, including services from FlixBus, Wanda Coach, Greyhound.
What is the earliest and latest departure time for the bus from New York City to Greenville?
The earliest bus departs from New York City to Greenville at 1:30am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from New York City to Greenville?
A bus trip from New York City to Greenville generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from New York City to Greenville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from New York City to Greenville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from New York City to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from New York City to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/25
$130
11/26
$130
Today
$130
11/28
$130
11/29
$130
11/30
$130
12/01
$130
12/02
$112
The cheapest trip from New York City to Greenville, SC was searched and found on Dec 2, 2025 with a price of $112
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to Greenville, SC, as early as possible.
You can expect to pay from $112 to $342 for a bus ticket from New York City to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $112 which is on 2025-12-02.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from New York City to Greenville, SC?
The bus is the cheapest travel choice for this destination