Bus from New York City to Greenville, SC: Tickets & Schedules

Next bus departures

Next departures for New York City to Greenville on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Wanda CoachBus
103 Canal St
1111 Woodruff RoadCheapestFastest
Wanda CoachBus
103 Canal St
1111 Woodruff RoadNo tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
1116 Woodruff RdNo tags
Greyhound Lines, Inc.Bus
New York Port Authority
1116 Woodruff RdNo tags
FlixBusBus
NYC Midtown (31st St & 8th Ave)
1116 Woodruff RdNo tags

Last refresh of the prices: Yesterday at 3:05 PM EST.

Compare 2 ways to go from New York City to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 15 hours 24 minutes and with fares starting at just $153, it presents an excellent value for a comfortable ride.

1train per day
15h 24mAverage Duration
613 milesDistance
90kgCO₂ emissions
Average Price$80 - $346Average Duration17h 10m
25kg CO₂e
Average Price$153 - $320Average Duration15h 24m
90kg CO₂e

Frequently asked questions about traveling from New York City to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from New York City to Greenville?

    The cheapest bus tickets from New York City to Greenville start from $80. The average price for this route is around $123. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from New York City to Greenville?

    The average bus trip duration from New York City to Greenville is 17h 10m, covering a distance of 615 miles (991 km). The quickest bus can get you there in 13h and is operated by Wanda Coach.

  3. Which bus companies service the New York City to Greenville route?

    Several major bus companies operate on this route with 33 buses available per day, including services from FlixBus, Wanda Coach, Greyhound.

  4. What is the earliest and latest departure time for the bus from New York City to Greenville?

    The earliest bus departs from New York City to Greenville at 1:30am. And the latest bus departs at 11:59pm.

  5. What are the CO₂ emissions for the bus trip from New York City to Greenville?

    A bus trip from New York City to Greenville generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from New York City to Greenville?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from New York City to Greenville?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from New York City to Greenville?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from New York City to Greenville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/25
$130
11/26
$130
Today
$130
11/28
$130
11/29
$130
11/30
$130
12/01
$130
12/02
$112
busbud logoThe cheapest trip from New York City to Greenville, SC was searched and found on Dec 2, 2025 with a price of $112

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to Greenville, SC, as early as possible.

You can expect to pay from $112 to $342 for a bus ticket from New York City to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $112 which is on 2025-12-02.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from New York City to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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