Bus from Charleston, SC, US to Greenville, SC: Tickets & Schedules

Previously seen trips

Next departures for Charleston to Greenville on November 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
4565 Gaynor Ave, North Charleston
1116 Woodruff RdNo tags
GreyhoundBus
4565 Gaynor Ave, North Charleston
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
4565 Gaynor Ave, North Charleston
1116 Woodruff RdNo tags
GreyhoundBus
4565 Gaynor Ave, North Charleston
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
4565 Gaynor Ave, North Charleston
1116 Woodruff RdNo tags

Compare 2 ways to go from Charleston to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 19 hours 50 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.

1bus per day
19h 50mAverage Duration
189 milesDistance
8kgCO₂ emissions
Average Price$91 - $188Average Duration19h 50m
8kg CO₂e
Average Price$148 - $588Average Duration20h 9m
29kg CO₂e

Frequently asked questions about traveling from Charleston, SC, US to Greenville, SC by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/25
No data
11/26
$114
Today
No data
11/28
No data
11/29
No data
11/30
No data
12/01
No data
12/02
No data
busbud logoThe cheapest trip from Charleston, SC, US to Greenville, SC was searched and found on Nov 26, 2025 with a price of $114

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Greenville, SC, as early as possible.

What's the cheapest way to go from Charleston, SC, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

People from around the world trust Busbud