Find coaches from Charleston, SC, US to Greenville, SC

Next departures

Next departures from Charleston to Greenville on 6 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
    4565 Gaynor Ave, North Charleston
    1116 Woodruff RdCheapestFastest

    Last refresh of the prices: Yesterday at 10:34 PM EST.

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    Compare 2 ways to travel from Charleston to Greenville

    We recommend taking the bus

    Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 40 minutes and with fares starting at just R 1 404, it presents an excellent value for a comfortable ride.

    1bus per day
    18h 40mAverage duration
    305 kmDistance
    8kgCO₂ emissions
    Average priceR 1 404 - R 2 475Average duration18h 40m
    8kg CO₂e
    Average priceR 2 738 - R 9 684Average duration1d 7h
    29kg CO₂e

    Bus Charleston, SC, US to Greenville, SC: Trip Overview

    Average ticket priceR 1 984
    Average bus trip duration18h 40m
    Number of daily buses1
    Earliest bus departure13:55
    Distance304 km
    Latest bus departure15:15

    Charleston to Greenville Bus

    With Busbud, comparing and booking tickets for a bus from Charleston to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

    We make it our job to connect you with the most dependable bus companies that cover bus service from Charleston to Greenville.

    Whether it is cheap bus tickets or more luxurious buses going to Greenville from Charleston, we help you find what you're looking for based on how much of a budget you have.

    Frequently asked questions on the trip Charleston, SC, US - Greenville, SC

    1. How much does a bus ticket from Charleston to Greenville cost?

      The bus ticket price from Charleston to Greenville starts at R 1 404. The best way to find cheap bus tickets from Charleston to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

    2. How long is the bus ride from Charleston to Greenville?

      The average travel time between Charleston and Greenville is around 18h 40m, although the fastest bus will take about 15h 50m. This is the time it takes to travel the 324 km that separates the two cities.

    3. How many daily bus connections are there between Charleston and Greenville?

      The number of buses from Charleston to Greenville can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Charleston to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

    4. Which bus companies travel from Charleston to Greenville?

      When taking the bus from Charleston to Greenville, you can travel comfortably and safely with FlixBus, Greyhound.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    03/11
    No data
    04/11
    R 1 704
    Today
    No data
    06/11
    No data
    07/11
    No data
    08/11
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    09/11
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    10/11
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    busbud logoThe cheapest trip from Charleston, SC, US to Greenville, SC was searched and found on 04 Nov 2025 with a price of R 1 704

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Greenville, SC as early as possible.

    About Bus Travel

    Bus Travel Tips

    Meet and talk to locals at the bus stations while travelling from Charleston to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

    From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Charleston to Greenville.

    Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to Greenville.

    Make a music playlist for your bus ride from Charleston to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

    Did you know?

    Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

    The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

    9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

    What's the cheapest way to go from Charleston, SC, US to Greenville, SC?

    busbud logoThe bus is the cheapest travel choice for this destination

    Will you be returning to Charleston, SC, US by bus?

    Bus from Greenville, SC to Charleston, SC, US

    You can also go to Greenville, SC by train

    Train from Charleston, SC, US to Greenville, SC

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