Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 4565 Gaynor Ave, North Charleston | 1116 Woodruff Rd | CheapestFastest |
Last refresh of the prices: Today at 1:04 PM EST.
Compare 2 ways to go from Charleston to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 19 hours 50 minutes, and with fares starting at just $130, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and Greenville?
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
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Frequently asked questions about travelling from Charleston, SC, US to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charleston to Greenville?
The cheapest bus tickets from Charleston to Greenville start from $130. The average price for this route is around $178. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to Greenville?
The average bus travel time from Charleston to Greenville is 19h 50m, covering a distance of 305 km. The quickest bus can get you there in 16h 20m and is operated by FlixBus.
Which bus companies service the Charleston to Greenville route?
What are the earliest and latest departure times for the bus from Charleston to Greenville?
The earliest bus departs from Charleston to Greenville at 11:15am. And the latest bus departs at 1:55pm.
What are the CO₂ emissions for the bus trip from Charleston to Greenville?
A bus trip from Charleston to Greenville generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Charleston to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Charleston to Greenville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Charleston to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charleston to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, SC, US to Greenville, SC was searched and found on Nov 26, 2025 with a price of $163To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Greenville, SC, as early as possible.
What's the cheapest way to go from Charleston, SC, US to Greenville, SC?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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