How much is the bus ticket from Orlando to Greenville?

The cheapest bus tickets from Orlando to Greenville start from $69. The average price for this route is around $107. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Orlando to Greenville?

The average bus trip duration from Orlando to Greenville is 11h 55m, covering a distance of 437 miles (704 km). The quickest bus can get you there in 10h 25m and is operated by Greyhound .

Which bus companies service the Orlando to Greenville route?

Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Orlando to Greenville?

The earliest bus departs from Orlando to Greenville at 4:45am. And the latest bus departs at 10:55pm.

What are the CO₂ emissions for the bus trip from Orlando to Greenville?

A bus trip from Orlando to Greenville generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Orlando to Greenville?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11380 reviews.

Which bus company has the best Wi-Fi from Orlando to Greenville?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Orlando to Greenville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Orlando to Greenville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Orlando to Greenville from $73 | Refundable Tickets

Next bus departures

Next departures for Orlando to Greenville on December 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:55pm	Orlando Bus Station	11h 45m	10:40am	1116 Woodruff Rd	Cheapest
	Bus	8:40pm	Orlando Bus Station	10h 25m	7:05am	1116 Woodruff Rd	Fastest
	Bus	10:00am	Orlando Bus Station	11h 55m	9:55pm	1116 Woodruff Rd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	The Florida Mall	17h 5m	7:05am	1116 Woodruff Rd	No tags

Next departures for Orlando to Greenville on December 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:00am	Orlando Bus Station	11h 55m	9:55pm	1116 Woodruff Rd	Cheapest
	Bus	8:40pm	Orlando Bus Station	10h 25m	7:05am	1116 Woodruff Rd	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	10:55pm	Orlando Bus Station	11h 45m	10:40am	1116 Woodruff Rd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	The Florida Mall	17h 5m	7:05am	1116 Woodruff Rd	No tags

Next departures for Orlando to Greenville on December 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	The Florida Mall	17h 5m	7:05am	1116 Woodruff Rd	Cheapest
	Bus	8:40pm	Orlando Bus Station	10h 25m	7:05am	1116 Woodruff Rd	Fastest
	Bus	10:00am	Orlando Bus Station	11h 55m	9:55pm	1116 Woodruff Rd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:55pm	Orlando Bus Station	11h 45m	10:40am	1116 Woodruff Rd	No tags

Next departures for Orlando to Greenville on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:00am	Orlando Bus Station	11h 55m	9:55pm	1116 Woodruff Rd	Cheapest
	Bus	8:40pm	Orlando Bus Station	10h 25m	7:05am	1116 Woodruff Rd	Fastest
	Bus	4:45am	Orlando Bus Station	14h 55m	7:40pm	1116 Woodruff Rd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:55pm	Orlando Bus Station	11h 45m	10:40am	1116 Woodruff Rd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	The Florida Mall	17h 5m	7:05am	1116 Woodruff Rd	No tags

Last refresh of the prices: Last Friday at 12:19 PM EST.

Compare 2 ways to go from Orlando to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 11 hours 55 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.

5bus per day

11h 55mAverage Duration

437 milesDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$69 - $206	Average Duration11h 55m	CO₂ emissions 18kg CO₂e
Train	Average Price$167 - $1,044	Average Duration1d 10h	CO₂ emissions 65kg CO₂e

Where are the popular stops in Orlando and Greenville?

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Compare bus companies

FlixBus

3.5/511,484 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,410 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Orlando to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Orlando to Greenville?
The cheapest bus tickets from Orlando to Greenville start from $69. The average price for this route is around $107. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Greenville?
The average bus trip duration from Orlando to Greenville is 11h 55m, covering a distance of 437 miles (704 km). The quickest bus can get you there in 10h 25m and is operated by Greyhound.
Which bus companies service the Orlando to Greenville route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Orlando to Greenville?
The earliest bus departs from Orlando to Greenville at 4:45am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Orlando to Greenville?
A bus trip from Orlando to Greenville generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Orlando to Greenville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Orlando to Greenville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Orlando to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/28

No data

11/29

$129

Today

$223

12/01

$116

12/02

$106

12/03

$87

12/04

$102

12/05

$102

The cheapest trip from Orlando to Greenville, SC was searched and found on Dec 3, 2025 with a price of $87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Greenville, SC, as early as possible.

You can expect to pay from $87 to $231 for a bus ticket from Orlando to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $87 which is on 2025-12-03.

Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.