Bus Tickets from New Orleans to Greenville, SC

Next departures

Next departures for New Orleans to Greenville on November 7
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		New Orleans Bus Station
    		1116 Woodruff RdCheapestFastest
    Greyhound Lines, Inc.
      		New Orleans Bus Station
      		1116 Woodruff RdNo tags
      FlixBus + Greyhound Lines, Inc.
        		New Orleans Bus Station
        		1116 Woodruff RdNo tags

        Last refresh of the prices: Yesterday at 11:18 AM CST.

        Compare 2 ways to go from New Orleans to Greenville

        We recommend taking the bus

        Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 17 hours 5 minutes and with fares starting at just $61, it presents an excellent value for a comfortable ride.

        2bus per day
        17h 5mAverage Duration
        564 milesDistance
        23kgCO₂ emissions
        Bus
        		Average Price$61 - $227Average Duration17h 5m
        23kg CO₂e
        Train
        		Average Price$134 - $234Average Duration16h 8m
        82kg CO₂e

        Bus New Orleans to Greenville, SC: Trip Overview

        Average ticket price$132
        Average bus trip duration17h 5m
        Number of daily buses2
        Earliest bus departure1:00pm
        Distance564 miles (909 km)
        Latest bus departure11:15pm

        New Orleans to Greenville Bus

        With Busbud, comparing and booking tickets for a bus from New Orleans to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

        We make sure you can find a bus service from New Orleans to Greenville from the most reliable bus companies operating this trip.

        Discover how much the bus trip from New Orleans to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

        Frequently asked questions for your trip New Orleans - Greenville, SC

        Find cheapest prices for buses

        Price is for a one-way ticket for one passenger and based on past searches.

        Best price found
        11/04
        $137
        11/05
        $128
        Today
        $153
        11/07
        $128
        11/08
        $89
        11/09
        $91
        11/10
        $93
        11/11
        $97
        busbud logoThe cheapest trip from New Orleans to Greenville, SC was searched and found on Nov 8, 2025 with a price of $89

        To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville, SC, as early as possible.

        You can expect to pay from $89 to $156 for a bus ticket from New Orleans to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $89 which is on 2025-11-08.

        About Bus Travel

        Bus Travel Tips

        Meet and talk to locals at the bus stations while traveling from New Orleans to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

        Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Greenville, get comfy and count the stars.

        Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from New Orleans to Greenville will emit less CO2 than a car or an airplane.

        Make a music playlist for your bus ride from New Orleans to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

        Did you know?

        Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

        Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

        It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

        What's the cheapest way to go from New Orleans to Greenville, SC?

        busbud logoThe bus is the cheapest travel choice for this destination

        Will you be returning to New Orleans by bus?

        Bus from Greenville, SC to New Orleans

        You can also go to Greenville, SC by train

        Train from New Orleans to Greenville, SC

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