Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | New Orleans Bus Station | 1116 Woodruff Rd | CheapestFastest | ||||
| Bus | New Orleans Bus Station | 1116 Woodruff Rd | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | New Orleans Bus Station | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Today at 9:31 AM CST.
Compare 2 ways to go from New Orleans to Greenville
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 17 hours 5 minutes, and with fares starting at just $87, it presents an excellent value for a comfortable ride.
2bus per day
17h 5mAverage Duration
910 kmDistance
23kgCO₂ emissions
Compare bus companies
US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Where are the popular stops in New Orleans and Greenville?
Stops in New Orleans
Stops in Greenville
Frequently asked questions about travelling from New Orleans to Greenville, SC by bus
What is the distance between New Orleans and Greenville?
New Orleans and Greenville are 905 km (561 miles) apart.
What are the departure and arrival locations for buses traveling from New Orleans to Greenville?
Buses departing from Union Passenger Terminal in New Orleans will take you to Guadalajara Supermarket Bus Stop in Greenville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-10
$224
11-11
$224
Today
$220
11-13
$207
11-14
$172
11-15
$158
11-16
$156
11-17
$153
The cheapest trip from New Orleans to Greenville, SC was searched and found on Nov 17, 2025 with a price of $153To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville, SC, as early as possible.
You can expect to pay from $153 to $247 for a bus ticket from New Orleans to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $153 which is on 2025-11-17.
What's the cheapest way to go from New Orleans to Greenville, SC?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting New Orleans
Buses Leaving from New Orleans
- Bus from New Orleans to Houston
- Bus New Orleans - Nashville
- New Orleans - St. Louis
- Bus from New Orleans to Biloxi
- Bus New Orleans - Memphis
- New Orleans - Tampa
- Bus from New Orleans to Fort Pierce
- Bus New Orleans - Daytona Beach
- New Orleans - Port Saint Lucie
- Bus from New Orleans to Atlanta
- Bus New Orleans - St. Petersburg
- New Orleans - Spartanburg
- Bus from New Orleans to Meridian
- Bus New Orleans - Petersburg
- New Orleans - West Palm Beach
Buses Going to New Orleans
- Bus from Riverside to New Orleans
- Bus St. Louis - New Orleans
- Dallas - New Orleans
- Bus from Las Vegas to New Orleans
- Bus Memphis - New Orleans
- Hamilton - New Orleans
- Bus from Burlington to New Orleans
- Bus Houston - New Orleans
- Portland - New Orleans
- Bus from San Angelo to New Orleans
- Bus Fort Pierce - New Orleans
- Charleston - New Orleans
- Bus from Johnstown to New Orleans
- Bus Detroit - New Orleans
- Austin - New Orleans
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Bus Greenville - Charleston
- Greenville - Spartanburg
- Bus from Greenville to Greensboro
- Bus Greenville - Miami
- Greenville - Chicago
- Bus from Greenville to Valparaiso
- Bus Greenville - Brattleboro
- Greenville - Crockett
- Bus from Greenville to Colonial Heights
- Bus Greenville - Fitchburg
- Greenville - Statesboro
- Bus from Greenville to Atlanta
- Bus Greenville - Vail
- Greenville - LaPlace
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Bus Burlington - Greenville
- Nashville - Greenville
- Bus from Knoxville to Greenville
- Bus Savannah - Greenville
- Orlando - Greenville
- Bus from New Orleans to Greenville
- Bus Rocky Mount - Greenville
- Sandusky - Greenville
- Bus from Brattleboro to Greenville
- Bus Phoenix - Greenville
- Charlotte - Greenville
- Bus from Statesboro to Greenville
- Bus Oceanside - Greenville
- Crockett - Greenville
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Philadelphia to New York City
- Bus Niagara Falls - New York City
- Buffalo - New York City
- Bus from New York City to Fleischmanns
- Bus Baton Rouge - New Orleans
- Baltimore - New York City
- Bus from Atlanta to Savannah
- Bus Albany - New York City
- New York City - Burlington
- Bus from Las Vegas to Los Angeles
- Bus Los Angeles - San Diego
- Detroit - Chicago