How much is the bus ticket from St. Louis to Chicago?

The cheapest bus tickets from St. Louis to Chicago start from $38. The average price for this route is around $47. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from St. Louis to Chicago?

The average bus trip duration from St. Louis to Chicago is 6h 25m, covering a distance of 254 miles (409 km). The quickest bus can get you there in 4h 50m and is operated by FlixBus .

Which bus companies service the St. Louis to Chicago route?

Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus , Greyhound , Burlington Trailways , Amtrak .

What is the earliest and latest departure time for the bus from St. Louis to Chicago?

The earliest bus departs from St. Louis to Chicago at 2:00am. And the latest bus departs at 11:30pm.

What are the CO₂ emissions for the bus trip from St. Louis to Chicago?

A bus trip from St. Louis to Chicago generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from St. Louis to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways , with an average rating of 4.2 out of 5 stars based on 20 reviews.

Which bus company has the best Wi-Fi from St. Louis to Chicago?

Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

Which bus company has the most timely service from St. Louis to Chicago?

According to Busbud traveller reviews, the most timely bus company on this route is Burlington Trailways , with a punctuality rating of 5.0 out of 5 stars.

Which bus company has the cleanest buses from St. Louis to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways , with a cleanliness rating of 5.0 out of 5 stars.

Bus St. Louis to Chicago from $34 | Refundable Tickets

Next departures

Next departures for St. Louis to Chicago on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		11:30pm	Gateway Station	6h 15m	5:45am	Downtown Greyhound Station	Cheapest
		11:30pm	Gateway Station	5h 50m	5:20am	Chicago 95Th & Dan Ryan	Fastest

Next departures for St. Louis to Chicago on November 29
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:30pm	Gateway Station	5h 50m	5:20am	Chicago 95Th & Dan Ryan	CheapestFastest
8:45am	Gateway Station	11h 25m	8:10pm	Downtown Greyhound Station	No tags
11:30pm	Gateway Station	6h 15m	5:45am	Downtown Greyhound Station	No tags
1:55pm	Gateway Station	9h 40m	11:35pm	Downtown Greyhound Station	No tags
2:00am	Gateway Station	12h 10m	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for St. Louis to Chicago on November 30
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:30pm	Gateway Station	5h 50m	5:20am	Chicago 95Th & Dan Ryan	CheapestFastest
8:45am	Gateway Station	11h 25m	8:10pm	Downtown Greyhound Station	No tags
11:30pm	Gateway Station	6h 15m	5:45am	Downtown Greyhound Station	No tags
1:55pm	Gateway Station	9h 40m	11:35pm	Downtown Greyhound Station	No tags
2:00am	Gateway Station	12h 10m	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for St. Louis to Chicago on December 1
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:30am	Gateway Station	7h	4:30pm	Downtown Greyhound Station	Cheapest
4:00pm	Gateway Station	5h 50m	9:50pm	Chicago 95Th & Dan Ryan	Fastest
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags
4:00pm	Gateway Station	6h 15m	10:15pm	Downtown Greyhound Station	No tags
2:00am	Gateway Station	12h 10m	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for St. Louis to Chicago on December 2
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
4:00pm	Gateway Station	6h 15m	10:15pm	Downtown Greyhound Station	Cheapest
4:00pm	Gateway Station	5h 50m	9:50pm	Chicago 95Th & Dan Ryan	Fastest
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags
8:45am	Gateway Station	11h 25m	8:10pm	Downtown Greyhound Station	No tags
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags

Next departures for St. Louis to Chicago on December 3
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
1:55pm	Gateway Station	9h 5m	11:00pm	Chicago 95Th & Dan Ryan	CheapestFastest
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags
2:00am	Gateway Station	12h 35m	2:35pm	Downtown Greyhound Station	No tags
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags
8:45am	Gateway Station	11h 25m	8:10pm	Downtown Greyhound Station	No tags

Next departures for St. Louis to Chicago on December 4
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:30am	Gateway Station	7h	4:30pm	Downtown Greyhound Station	Cheapest
11:30pm	Gateway Station	5h 50m	5:20am	Chicago 95Th & Dan Ryan	Fastest
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags
1:55pm	Gateway Station	9h 40m	11:35pm	Downtown Greyhound Station	No tags
11:30pm	Gateway Station	6h 15m	5:45am	Downtown Greyhound Station	No tags

Next departures for St. Louis to Chicago on December 5
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:30am	Gateway Station	7h	4:30pm	Downtown Greyhound Station	Cheapest
4:00pm	Gateway Station	5h 50m	9:50pm	Chicago 95Th & Dan Ryan	Fastest
11:00pm	Gateway Station	10h 15m	9:15am	Chicago (Union Station), IL	No tags
4:00pm	Gateway Station	6h 15m	10:15pm	Downtown Greyhound Station	No tags
2:00am	Gateway Station	12h 10m	2:10pm	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Today at 3:08 PM CST.

Compare 2 ways to go from St. Louis to Chicago

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 5 hours 5 minutes and with fares starting at just $30, it presents an excellent value for a comfortable ride.

5train per day

5h 5mAverage Duration

262 milesDistance

38kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$38 - $187	Average Duration6h 25m	CO₂ emissions 10kg CO₂e
Train	Average Price$30 - $98	Average Duration5h 5m	CO₂ emissions 38kg CO₂e

Where are the popular stops in St. Louis and Chicago?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

FlixBus

3.5/511,470 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,407 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound St. Louis Chicago recent customer reviews

My trip was changed then cancelled and the next bus took 2 hrs . My connection to complete my trip made me arrive at my final destination at 4 am to an empty station where I couldn't get any assistance. Couldn't get a taxi at that hour there. It was a very horrible experience.

Raydell W.

July 3, 2023

My first time from along time to many stops little confusing if we were close or what time we really will be in Chicago in all Ok!

Shelia S.

July 18, 2019

Very professional and courteous. Actually, quite a bit more professional and less stressful than air travel presently. Pleasantly surprised!

Laura M.

October 18, 2018

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

Wifi5

Amtrak

4/55,611 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Users have praised the service for being on time, comfortable, and convenient with friendly conductors. However, there were concerns about inconsistent behavior from staff towards passengers of different races during ticket checks and upon arrival.

Amtrak St. Louis Chicago recent customer reviews

Smooth ride. The man who did our tickets from St. Louis we noticed after checking white people's tickets he said thanks and have a great day. To black people he said nothing. Then upon arriving in Chicago that man offered no one a hand down or said goodbye.

Yvonne H.

September 27, 2024

Fabulous! Train is the way to go for this distance!! On time, comfortable, friendly conductors, and SO convenient!

Kendra H.

April 3, 2024

Good but train was cancelled and coming with bus. I pay too much money

Anshul P.

December 23, 2024

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from St. Louis to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from St. Louis to Chicago?
The cheapest bus tickets from St. Louis to Chicago start from $38. The average price for this route is around $47. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Chicago?
The average bus trip duration from St. Louis to Chicago is 6h 25m, covering a distance of 254 miles (409 km). The quickest bus can get you there in 4h 50m and is operated by FlixBus.
Which bus companies service the St. Louis to Chicago route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound, Burlington Trailways, Amtrak.
What is the earliest and latest departure time for the bus from St. Louis to Chicago?
The earliest bus departs from St. Louis to Chicago at 2:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Chicago?
A bus trip from St. Louis to Chicago generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from St. Louis to Chicago?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from St. Louis to Chicago?
According to Busbud traveller reviews, the most timely bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/26

$73

11/27

$67

Today

$57

11/29

$71

11/30

$82

12/01

$42

12/02

$41

12/03

$44

The cheapest trip from St. Louis to Chicago was searched and found on Dec 2, 2025 with a price of $41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Chicago, as early as possible.

You can expect to pay from $41 to $270 for a bus ticket from St. Louis to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-12-02.

Usually Greyhound, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.