Next departures for Saint Paul to Chicago on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Downtown Greyhound Station
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Union Depot
Chicago 95Th & Dan Ryan
No tags
Next departures for Saint Paul to Chicago on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Downtown Greyhound Station
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Chicago (Union Station), IL
No tags
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Next departures for Saint Paul to Chicago on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Downtown Greyhound Station
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Chicago (Union Station), IL
No tags
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Next departures for Saint Paul to Chicago on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Downtown Greyhound Station
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Chicago (Union Station), IL
No tags
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Next departures for Saint Paul to Chicago on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Chicago 95Th & Dan Ryan
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Chicago (Union Station), IL
No tags
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Next departures for Saint Paul to Chicago on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Expreso + Tornado Bus
178 Cesar Chavez St
West Chicago, (IL - Rapid Net Cafe Internet)
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Greyhound Lines, Inc. + FlixBus
Union Depot
Chicago 95Th & Dan Ryan
No tags
Next departures for Saint Paul to Chicago on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Downtown Greyhound Station
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Chicago (Union Station), IL
No tags
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Next departures for Saint Paul to Chicago on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Depot
Downtown Greyhound Station
Cheapest
Union Depot
N Cumberland Ave
Fastest
Union Depot
Chicago (Union Station), IL
No tags
Union Depot
Downtown Greyhound Station
No tags
Union Depot
Downtown Greyhound Station
No tags
Last refresh of the prices: Yesterday at 11:47 PM CST.
Compare 2 ways to go from Saint Paul to Chicago
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 9 hours 14 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Saint Paul Chicago recent customer reviews
Horrible. Greyhound cancelled my trip and forced me into a voucher that is not needed
1 out of 5 stars
Anthony S.
Your busdriver pulled off as I was coming up the stairs and my nephew told him we was coming but he pulled off.So we had to change our ticket until a later time.So my brother will miss work on Monday
1 out of 5 stars
Linda B.
I was not please at all. i am disability my feet was very big just by sitting there all that time I am very upset. And your bus r very ruled I just was asking question that day was no help at all.
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
FlixBus Saint Paul Chicago recent customer reviews
Driver never called a stop nor was he cordial, no greeting non responsive to a first time riders inquiry. Not a good rep of the company. He was very cold & stand offish
Customers have praised the wonderful trip with beautiful views, friendly and helpful staff, and comfortable seating. The double decker bus offers great seats with lots of legroom, big windows for a fantastic view, and delicious breakfast.
Amtrak Saint Paul Chicago recent customer reviews
Wonderful trip. Views were beautiful. Staff friendly and helpful. Comfortable as well.
5 out of 5 stars
Patricia W.
Great seats with lots of legroom, comfortable chairs, big windows, double decker so had a great view and breakfast was delicious.
A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,2 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $80 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.
Frequently asked questions about traveling from Saint Paul, US to Chicago by bus
What is the travel distance from Saint Paul to Chicago?
The distance separating Saint Paul and Chicago is 347 miles (559 km).
What are the departure and arrival stations when taking the bus from Saint Paul to Chicago?
The majority of buses traveling from Saint Paul to Chicago start their journey at 178 Cesar Chavez St and wind up at Downtown Greyhound Station. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Museum of Science and Industry, Brookfield Zoo, Architectural River Cruise, The Field Museum and Lincoln Park Conservatory.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$62
11/20
$68
Today
$77
11/22
$62
11/23
$66
11/24
$77
11/25
$101
11/26
$114
The cheapest trip from Saint Paul, US to Chicago was searched and found on Nov 19, 2025 with a price of $62
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Saint Paul, US to Chicago, as early as possible.
You can expect to pay from $62 to $207 for a bus ticket from Saint Paul, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $62 which is on 2025-11-22.
Usually Amtrak, Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Saint Paul, US to Chicago?
The bus is the cheapest travel choice for this destination