Bus Tickets from St. Louis to Milwaukee

Next departures

Next departures for St. Louis to Milwaukee on November 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Mitchell MKE AirportCheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.Fastest
Amtrak
Gateway Station
MKE Airport - TrainsNo tags
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.No tags
FlixBus
Gateway Station
Milwaukee Mitchell MKE AirportNo tags

Last refresh of the prices: Yesterday at 1:16 PM CST.

Compare 2 ways to go from St. Louis to Milwaukee

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Milwaukee. The journey takes about 8 hours 18 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.

8train per day
8h 18mAverage Duration
327 milesDistance
48kgCO₂ emissions
Average Price$53 - $179Average Duration14h 15m
13kg CO₂e
Average Price$51 - $390Average Duration8h 18m
48kg CO₂e

Frequently asked questions about traveling from St. Louis to Milwaukee by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/19
$83
11/20
$124
Today
$133
11/22
$115
11/23
$104
11/24
$83
11/25
$69
11/26
$80
busbud logoThe cheapest trip from St. Louis to Milwaukee was searched and found on Nov 25, 2025 with a price of $69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Milwaukee, as early as possible.

You can expect to pay from $69 to $335 for a bus ticket from St. Louis to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-11-25.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from St. Louis to Milwaukee?

busbud logoThe bus is the cheapest travel choice for this destination

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