Next departures for St. Louis to Milwaukee on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Milwaukee Mitchell MKE Airport
No tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Goerke's Corners Park & Ride (Brookfield)
No tags
Next departures for St. Louis to Milwaukee on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Mitchell MKE Airport
Cheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
Fastest
Gateway Station
MKE Airport - Trains
No tags
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Milwaukee Mitchell MKE Airport
No tags
Next departures for St. Louis to Milwaukee on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Gateway Station
Goerke's Corners Park & Ride (Brookfield)
Cheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
Fastest
Gateway Station
Intermodal Station
No tags
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Milwaukee Mitchell MKE Airport
No tags
Next departures for St. Louis to Milwaukee on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Gateway Station
Milwaukee Mitchell MKE Airport
Cheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
Fastest
Gateway Station
Intermodal Station
No tags
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Goerke's Corners Park & Ride (Brookfield)
No tags
Next departures for St. Louis to Milwaukee on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Gateway Station
Milwaukee Mitchell MKE Airport
Cheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
Fastest
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Goerke's Corners Park & Ride (Brookfield)
No tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Next departures for St. Louis to Milwaukee on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Milwaukee Mitchell MKE Airport
No tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Goerke's Corners Park & Ride (Brookfield)
No tags
Next departures for St. Louis to Milwaukee on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Gateway Station
Goerke's Corners Park & Ride (Brookfield)
Cheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
Fastest
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Gateway Station
Milwaukee Mitchell MKE Airport
No tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.
No tags
Last refresh of the prices: Yesterday at 1:16 PM CST.
Compare 2 ways to go from St. Louis to Milwaukee
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Milwaukee. The journey takes about 8 hours 18 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5597 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $124
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound St. Louis Milwaukee recent customer reviews
There was was 1 hour and 15 minutes late. No notifications were sent out .
Frequently asked questions about traveling from St. Louis to Milwaukee by bus
What is the distance between St. Louis and Milwaukee?
About 328 miles (528 km) separate St. Louis and Milwaukee.
What are the departure and arrival stations when taking the bus from St. Louis to Milwaukee?
If you're headed to Milwaukee from St. Louis, chances are that your bus will leave from Gateway Station and arrive at Milwaukee Airport. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$83
11/20
$124
Today
$133
11/22
$115
11/23
$104
11/24
$83
11/25
$69
11/26
$80
The cheapest trip from St. Louis to Milwaukee was searched and found on Nov 25, 2025 with a price of $69
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Milwaukee, as early as possible.
You can expect to pay from $69 to $335 for a bus ticket from St. Louis to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-11-25.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from St. Louis to Milwaukee?
The bus is the cheapest travel choice for this destination