How much is the bus ticket from Indianapolis to Greenville?

The cheapest bus tickets from Indianapolis to Greenville start from $117. The average price for this route is around $170. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Indianapolis to Greenville?

The average bus trip duration from Indianapolis to Greenville is 16h 15m, covering a distance of 401 miles (646 km). The quickest bus can get you there in 15h 15m and is operated by Greyhound .

Which bus companies service the Indianapolis to Greenville route?

Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Indianapolis to Greenville?

The earliest bus departs from Indianapolis to Greenville at 3:40am. And the latest bus departs at 11:30pm.

What are the CO₂ emissions for the bus trip from Indianapolis to Greenville?

A bus trip from Indianapolis to Greenville generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Indianapolis to Greenville?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Indianapolis to Greenville?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Indianapolis to Greenville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Indianapolis to Greenville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Indianapolis to Greenville from $117 | Refundable Tickets

Previously seen trips

Next departures for Indianapolis to Greenville on December 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	3:50pm	Indianapolis Bus Station	15h 45m	7:35am	1116 Woodruff Rd	No tags
Greyhound + FlixBus	Bus	6:25pm	Downtown Transit Center	15h 35m	10:00am	1116 Woodruff Rd	No tags
	Bus	7:55pm	Indianapolis Bus Station	19h 25m	3:20pm	1116 Woodruff Rd	No tags
Greyhound + FlixBus	Bus	8:10pm	Indianapolis Bus Station	20h 20m	4:30pm	1116 Woodruff Rd	No tags
	Bus	11:55pm	Downtown Transit Center	16h 35m	4:30pm	1116 Woodruff Rd	No tags

Compare 2 ways to go from Indianapolis to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 16 hours 15 minutes and with fares starting at just $117, it presents an excellent value for a comfortable ride.

4bus per day

16h 15mAverage Duration

401 milesDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$117 - $299	Average Duration16h 15m	CO₂ emissions 16kg CO₂e
Train	Average Price$223 - $1,046	Average Duration1d 5h	CO₂ emissions 58kg CO₂e

Where are the popular stops in Indianapolis and Greenville?

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Compare bus companies

Greyhound

3.5/587,462 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,804 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Indianapolis to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Indianapolis to Greenville?
The cheapest bus tickets from Indianapolis to Greenville start from $117. The average price for this route is around $170. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Greenville?
The average bus trip duration from Indianapolis to Greenville is 16h 15m, covering a distance of 401 miles (646 km). The quickest bus can get you there in 15h 15m and is operated by Greyhound.
Which bus companies service the Indianapolis to Greenville route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Indianapolis to Greenville?
The earliest bus departs from Indianapolis to Greenville at 3:40am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Indianapolis to Greenville?
A bus trip from Indianapolis to Greenville generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Indianapolis to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Greenville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Indianapolis to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.