How much is the bus ticket from Boston to Greenville?

The cheapest bus tickets from Boston to Greenville start from $106. The average price for this route is around $184. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Boston to Greenville?

The average bus trip duration from Boston to Greenville is 23h 40m, covering a distance of 797 miles (1285 km). The quickest bus can get you there in 20h 5m and is operated by FlixBus .

Which bus companies service the Boston to Greenville route?

Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Boston to Greenville?

The earliest bus departs from Boston to Greenville at 1:30am. And the latest bus departs at 9:50pm.

What are the CO₂ emissions for the bus trip from Boston to Greenville?

A bus trip from Boston to Greenville generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Boston to Greenville?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11638 reviews.

Which bus company has the best Wi-Fi from Boston to Greenville?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Boston to Greenville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Boston to Greenville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Boston to Greenville from $106 | Refundable Tickets

Next bus departures

Next departures for Boston to Greenville on December 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	3:05pm	Boston (South Station)	22h 10m	1:15pm	1116 Woodruff Rd	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:35pm	Boston (South Station)	1d	7:40pm	1116 Woodruff Rd	No tags
	Bus	8:55pm	Brookline	22h 45m	7:40pm	1116 Woodruff Rd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:50pm	Boston (South Station)	1d 10h	8:35am	1116 Woodruff Rd	No tags

Next departures for Boston to Greenville on December 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:30pm	Boston (South Station)	20h 5m	8:35am	1116 Woodruff Rd	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	3:05pm	Boston (South Station)	22h 10m	1:15pm	1116 Woodruff Rd	No tags
	Bus	1:30am	Brookline	1d 7h	8:35am	1116 Woodruff Rd	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:35pm	Boston (South Station)	1d	7:40pm	1116 Woodruff Rd	No tags
	Bus	8:55pm	Brookline	22h 45m	7:40pm	1116 Woodruff Rd	No tags

Next departures for Boston to Greenville on December 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	9:50pm	Boston (South Station)	1d 13h	10:50am	1116 Woodruff Rd	Cheapest
	Bus	12:30pm	Boston (South Station)	20h 5m	8:35am	1116 Woodruff Rd	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	3:05pm	Boston (South Station)	22h 10m	1:15pm	1116 Woodruff Rd	No tags
	Bus	4:45pm	Boston (South Station)	1d	5:20pm	1116 Woodruff Rd	No tags
	Bus	1:30am	Brookline	1d 7h	8:35am	1116 Woodruff Rd	No tags

Last refresh of the prices: Last Wednesday at 8:07 AM EST.

Compare 2 ways to go from Boston to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 20 hours 29 minutes and with fares starting at just $250, it presents an excellent value for a comfortable ride.

5train per day

20h 29mAverage Duration

799 milesDistance

117kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$106 - $420	Average Duration23h 40m	CO₂ emissions 32kg CO₂e
Train	Average Price$250 - $1,501	Average Duration20h 29m	CO₂ emissions 117kg CO₂e

Where are the popular stops in Boston and Greenville?

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Compare bus companies

FlixBus

3.5/511,744 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,453 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Boston, MA, US to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Boston to Greenville?
The cheapest bus tickets from Boston to Greenville start from $106. The average price for this route is around $184. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Greenville?
The average bus trip duration from Boston to Greenville is 23h 40m, covering a distance of 797 miles (1285 km). The quickest bus can get you there in 20h 5m and is operated by FlixBus.
Which bus companies service the Boston to Greenville route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Boston to Greenville?
The earliest bus departs from Boston to Greenville at 1:30am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Boston to Greenville?
A bus trip from Boston to Greenville generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Boston to Greenville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.
Which bus company has the best Wi-Fi from Boston to Greenville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Boston to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/24

$194

12/25

$171

Today

$192

12/27

$179

12/28

$237

12/29

$203

12/30

$162

12/31

$171

The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on Dec 30, 2025 with a price of $162

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Greenville, SC, as early as possible.

You can expect to pay from $162 to $290 for a bus ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $162 which is on 2025-12-30.