Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Amtrak + Amtrak Acela | Train | Back Bay Station | Greenville Station | No tags | ||||
Amtrak + Amtrak Acela | Train | Boston Route 128, MA | Greenville Station | No tags | ||||
Amtrak Acela + Amtrak | Train | Boston Route 128, MA | Greenville Station | No tags | ||||
 | Train | South Station | Greenville Station | No tags | ||||
| Train | Back Bay Station | Greenville Station | No tags |
Compare 2 ways to go from Boston to Greenville
Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 20 hours 29 minutes and with fares starting at just $216, it presents an excellent value for a comfortable ride.
Train Companies
Frequently asked questions about traveling from Boston, MA, US to Greenville, SC by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Boston to Greenville?
The cheapest train tickets from Boston to Greenville start from $216. The average price for this train route is around $485. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Boston to Greenville?
The average train ride duration from Boston to Greenville is 20h 29m, covering a distance of 800 miles (1290 km). The quickest train can get you there in 19h 59m and is operated by Amtrak Acela.
Which train operators service the Boston to Greenville route?
Several major train operators operate on this route with 5 trains available per day, including services from Amtrak, Amtrak Acela.
What is the earliest and latest departure time for the train from Boston to Greenville?
The earliest train departs from Boston to Greenville at 8:12am. And the latest train departs at 9:25am.
What is the best train operator from Boston to Greenville?
According to Busbud customers, the highest-rated train operator on this route is Amtrak Acela, with an average rating of 4.5 out of 5 stars based on 14 reviews.
Which train operator has the best Wi-Fi from Boston to Greenville?
Based on reviews on Busbud, the train operator Amtrak Acela has the best Wi-Fi rating with a score of 4.0.
Which train operator has the most timely service from Boston to Greenville?
According to Busbud traveller reviews, the most timely train operator on this route is Amtrak Acela, with a punctuality rating of 4.6 out of 5 stars.
Which train operator has the cleanest trains from Boston to Greenville?
According to Busbud traveller reviews, the train operator with the cleanest trains on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on Dec 19, 2025 with a price of $264To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Greenville, SC, as early as possible.
You can expect to pay from $264 to $984 for a train ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $264 which is on 2025-12-19.
