Bus from Boston, MA, US to Greenville, SC: Tickets & Timetables

Next bus departures

Next departures from Boston to Greenville on 7 January
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
1116 Woodruff RdCheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
1116 Woodruff RdNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
1116 Woodruff RdNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
1116 Woodruff RdNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
1116 Woodruff RdNo tags

Last refresh of the prices: Yesterday at 22:39 EST.

Compare 2 ways to travel from Boston to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 20 hours 39 minutes and with fares starting at just £149, it presents an excellent value for a comfortable ride.

4train per day
20h 39mAverage duration
799 milesDistance
117kgCO₂ emissions
Average price£75 - £285Average duration1d
32kg CO₂e
Average price£149 - £643Average duration20h 39m
117kg CO₂e

Frequently asked questions about travelling by bus from Boston, MA, US to Greenville, SC

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Boston to Greenville?

    The cheapest coach tickets from Boston to Greenville start from £75. The average price for this route is around £120. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Boston to Greenville?

    The average bus journey time from Boston to Greenville is 1d , covering a distance of 795 miles. The fastest bus can take you there in 20h 5m and is operated by FlixBus.

  3. Which bus companies service the Boston to Greenville route?

    Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Boston to Greenville?

    The earliest bus departs from Boston to Greenville at 01:30. And the latest bus departs at 21:50.

  5. What are the CO₂ emissions for the bus trip from Boston to Greenville?

    A bus journey from Boston to Greenville produces an estimated 32 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Boston to Greenville?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.

  7. Which company has the best Wi-Fi from Boston to Greenville?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Boston to Greenville?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Boston to Greenville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/01
£155
05/01
£91
Today
£81
07/01
No data
08/01
£117
09/01
£141
10/01
£103
11/01
£144
busbud logoThe cheapest trip from Boston, MA, US to Greenville, SC was searched and found on 6 Jan 2026 with a price of £81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Greenville, SC as early as possible.

You can expect to pay from £81 to £210 for a bus ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £103, which is on 2026-01-10.

What's the cheapest way to go from Boston, MA, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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