Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Gateway Station | Santa Ana Bus Station | No tags | |||||
| Gateway Station | Santa Ana Bus Station | No tags | |||||
| Saint Louis (Lambert Field) | Santa Ana Bus Station | No tags | |||||
FlixBus + Greyhound | Saint Louis (Lambert Field) | UC Irvine (Crawford Hall) | No tags | |||||
Greyhound + FlixBus | Saint Louis (Lambert Field) | Santa Ana Bus Station | No tags |
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Get from St. Louis to Santa Ana
The journey takes about 1 day, 20 hours 30 minutes, and with fares starting at just R 2 484, it presents an excellent value for a comfortable ride.
Bus St. Louis to Santa Ana, US: Trip Overview
Compare bus companies
Based on 87350 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 484
St. Louis to Santa Ana Bus
With Busbud, comparing and booking tickets for a bus from St. Louis to Santa Ana is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from St. Louis to Santa Ana will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from St. Louis, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in St. Louis and Santa Ana?
Frequently asked questions on the trip St. Louis - Santa Ana, US
How much does a bus ticket from St. Louis to Santa Ana cost?
The bus ticket price from St. Louis to Santa Ana starts at R 2 484. The best way to find cheap bus tickets from St. Louis to Santa Ana is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from St. Louis to Santa Ana?
The average travel time between St. Louis and Santa Ana is around 1d 20h, although the fastest bus will take about 1d 20h. This is the time it takes to travel the 2535 km that separates the two cities.
How many daily bus connections are there between St. Louis and Santa Ana?
The number of buses from St. Louis to Santa Ana can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from St. Louis to Santa Ana by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from St. Louis to Santa Ana?
When taking the bus from St. Louis to Santa Ana, you can travel comfortably and safely with Greyhound.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Santa Ana, US was searched and found on 05 Nov 2025 with a price of R 3 673To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Santa Ana, US as early as possible.
You can expect to pay from R 3 673 to R 4 802 for a bus ticket from St. Louis to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 673, which is on 2025-11-05.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from St. Louis to Santa Ana.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from St. Louis to Santa Ana, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Louis to Santa Ana.
Tune out to the fine sounds of your best music playlist on your bus trip from St. Louis to Santa Ana while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
- Bus from St. Louis to New Orleans
- Coach St. Louis - Kansas City
- Bus St. Louis - Kansas City
- Bus from St. Louis to Austin
- Coach St. Louis - Buffalo
- Bus St. Louis - Nashville
- Bus from St. Louis to Evergreen
- Coach St. Louis - Suisun City
- Bus St. Louis - Providence
- Bus from St. Louis to Henderson
- Coach St. Louis - Sterling City
- Bus St. Louis - Tyrone
- Bus from St. Louis to Joliet
- Coach St. Louis - Statesboro
- Bus St. Louis - Cheyenne
Buses Going to St. Louis
- Bus from New Orleans to St. Louis
- Coach Atlanta - St. Louis
- Bus Indianapolis - St. Louis
- Bus from Burlington to St. Louis
- Coach Omaha - St. Louis
- Bus Detroit - St. Louis
- Bus from New Iberia to St. Louis
- Coach College Station - St. Louis
- Bus Corning - St. Louis
- Bus from Cape Girardeau to St. Louis
- Coach Quincy - St. Louis
- Bus Austin - St. Louis
- Bus from Bald Knob to St. Louis
- Coach Waterloo - St. Louis
- Bus Naperville - St. Louis
Popular Buses Connecting Santa Ana
Buses Leaving from Santa Ana
- Bus from Santa Ana to Las Vegas
- Coach Santa Ana - Long Beach
- Bus Santa Ana - Los Angeles
- Bus from Santa Ana to Guadalajara
- Coach Santa Ana - Chihuahua
- Bus Santa Ana - Hermosillo
- Bus from Santa Ana to Indio
- Coach Santa Ana - Bellingham
- Bus Santa Ana - Tulare
- Bus from Santa Ana to Chicago
- Coach Santa Ana - Huntington Park
- Bus Santa Ana - Visalia
- Bus from Santa Ana to Conroe
- Coach Santa Ana - Ontario
- Bus Santa Ana - Lawton
Buses Going to Santa Ana
- Bus from Pueblo to Santa Ana
- Coach San Jose - Santa Ana
- Bus Anaheim - Santa Ana
- Bus from Long Beach to Santa Ana
- Coach Boston - Santa Ana
- Bus Chicago - Santa Ana
- Bus from Portland to Santa Ana
- Coach Albuquerque - Santa Ana
- Bus New York City - Santa Ana
- Bus from Victorville to Santa Ana
- Coach Delano - Santa Ana
- Bus Salinas - Santa Ana
- Bus from Temecula to Santa Ana
- Coach Conroe - Santa Ana
- Bus Jacksonville - Santa Ana
Popular routes in this country
- Bus from Buffalo to Niagara Falls
- Coach New York City - Fleischmanns
- Bus Memphis - Nashville
- Bus from Philadelphia to New Orleans
- Coach San Diego - Victorville
- Bus Las Vegas - Anaheim
- Bus from Houston to Brownsville
- Coach Los Angeles - Chico
- Bus Albany - Ridgewood
- Bus from Albany to New York City
- Coach New Orleans - Atlanta
- Bus New York City - Philadelphia
- Bus from Rancho Cucamonga to Los Angeles
- Coach Boynton Beach - Boston
- Bus Boston - Rockford