Find coaches from Santa Ana, US to Chicago

Previously seen journeys

Next departures from Santa Ana to Chicago on 5 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Santa Ana Bus Station
    		Downtown Greyhound StationNo tags
    Greyhound
      		Santa Ana Bus Station
      		537-517 W. Jackson BlvdNo tags
      Greyhound
        		Anaheim Regional Transportation Intermodal Center
        		537-517 W. Jackson BlvdNo tags
        Greyhound
          		Anaheim Regional Transportation Intermodal Center
          		Downtown Greyhound StationNo tags
          FlixBus + Greyhound
            		Anaheim Regional Transportation Intermodal Center
            		Chicago 95Th & Dan RyanNo tags

            Accepted payments

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            • Klarna (Pay over time)
            • Google Pay

            Get from Santa Ana to Chicago

            This route is served by bus only

            The journey takes about 2 days, 5 hours, and with fares starting at just R 3 971, it presents an excellent value for a comfortable ride.

            14bus per day
            2d 5hAverage duration
            2792 kmDistance
            70kgCO₂ emissions

            Bus Santa Ana, US to Chicago: Trip Overview

            Average ticket priceR 6 673
            Average bus trip duration2d 5h
            Number of daily buses14
            Earliest bus departure07:55
            Distance2791 km
            Latest bus departure21:40

            Santa Ana to Chicago Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Ana to Chicago.

            We make sure you can find a bus service from Santa Ana to Chicago from the most reliable bus companies operating this trip.

            Discover how much the bus trip from Santa Ana to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Santa Ana, US - Chicago

            1. How much does a bus ticket from Santa Ana to Chicago cost?

              The bus ticket price from Santa Ana to Chicago starts at R 3 971. The best way to find cheap bus tickets from Santa Ana to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Santa Ana to Chicago?

              The average travel time between Santa Ana and Chicago is around 2d 5h, although the fastest bus will take about 2d . This is the time it takes to travel the 2790 km that separates the two cities.

            3. How many daily bus connections are there between Santa Ana and Chicago?

              The number of buses from Santa Ana to Chicago can differ depending on the day of the week. On average, there are 14 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Ana to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Santa Ana to Chicago?

              When taking the bus from Santa Ana to Chicago, you can travel comfortably and safely with Greyhound.

            5. What are the departure and arrival stations when taking the bus from Santa Ana to Chicago?

              Buses travelling between Santa Ana and Chicago leave from Santa Ana Greyhound Bus Station or 602 S Main St and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            02/11
            No data
            03/11
            R 3 267
            Today
            No data
            05/11
            No data
            06/11
            No data
            07/11
            No data
            08/11
            No data
            09/11
            No data
            busbud logoThe cheapest trip from Santa Ana, US to Chicago was searched and found on 03 Nov 2025 with a price of R 3 267

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Chicago as early as possible.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Ana to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Ana to Chicago, get comfy and count the stars.

            Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Santa Ana to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Santa Ana to Chicago while indulging in miles on end of beautiful scenic views.

            Did you know?

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Will you be returning to Santa Ana, US by bus?

            Bus from Chicago to Santa Ana, US

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