Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | 537-517 W. Jackson Blvd | Santa Ana Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | 537-517 W. Jackson Blvd | UC Irvine (Crawford Hall) | No tags | ||||
FlixBus + Greyhound | Bus | 537-517 W. Jackson Blvd | Anaheim Regional Transportation Intermodal Center | No tags | ||||
Greyhound + FlixBus | Bus | Chicago 95Th & Dan Ryan | Santa Ana Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Chicago 95Th & Dan Ryan | UC Irvine (Crawford Hall) | No tags |
Get from Chicago to Santa Ana
The journey takes about 2 days, 4 hours 40 minutes, and with fares starting at just R 3 397, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Santa Ana?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- B
Chicago O'Hare International Airport
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
Compare bus companies
Based on 87516 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 3 397
Frequently asked questions about travelling from Chicago to Santa Ana, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Chicago to Santa Ana?
The cheapest bus tickets from Chicago to Santa Ana start at R 3 397. The average price for this route is around R 6 495. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Chicago to Santa Ana?
The average bus journey time from Chicago to Santa Ana is 2d 4h, covering a distance of 2785 km. The fastest bus gets you there in 2d 7h and is operated by Greyhound.
Which bus companies service the Chicago to Santa Ana route?
Several major bus companies operate on this route with 12 buses available per day.
What is the earliest and latest departure time for the bus from Chicago to Santa Ana?
The earliest bus departs from Chicago to Santa Ana at 00:40. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Chicago to Santa Ana?
A bus trip from Chicago to Santa Ana produces an estimated 70 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Santa Ana, US was searched and found on 23 Jan 2026 with a price of R 6 715To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Santa Ana, US as early as possible.
