Next departures from St. Louis to San Antonio on 20 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + Valley Transit
Bus
Gateway Station
San Antonio Bus Station
Cheapest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Gateway Station
San Antonio Bus Station
Fastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Gateway Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Pearl District
No tags
Bus
Gateway Station
San Antonio Bus Station
No tags
Next departures from St. Louis to San Antonio on 21 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Gateway Station
San Antonio Bus Station
CheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Gateway Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Valley Transit
Bus
Gateway Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Pearl District
No tags
Bus
Gateway Station
San Antonio Bus Station
No tags
Next departures from St. Louis to San Antonio on 22 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Pearl District
Cheapest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Gateway Station
San Antonio Bus Station
Fastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Gateway Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Valley Transit
Bus
Gateway Station
San Antonio Bus Station
No tags
Bus
Gateway Station
San Antonio Bus Station
No tags
Last refresh of the prices: Today at 15:59 CST.
Compare 2 ways to travel from St. Louis to San Antonio
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 22 hours 30 minutes and with fares starting at just £57, it presents an excellent value for a comfortable ride.
Based on 87382 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £57
Based on 11380 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £89
Frequently asked questions about travelling by bus from St. Louis to San Antonio, US
How far is San Antonio from St. Louis by coach?
The distance between St. Louis and San Antonio by coach is approximately 793 miles (1278 km).
What is the best way to go from St. Louis to San Antonio without flying?
You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
17/11
£165
18/11
£159
Today
£156
20/11
£184
21/11
£175
22/11
£147
23/11
£138
24/11
£113
The cheapest trip from St. Louis to San Antonio, US was searched and found on 24 Nov 2025 with a price of £113
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Antonio, US as early as possible.
You can expect to pay from £113 to £184 for a bus ticket from St. Louis to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at £113, which is on 2025-11-24.
The cheapest trip from St. Louis to San Antonio, US was searched and found on 24 Nov 2025 with a price of £113
