Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | San Antonio Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. + Valley Transit | Bus | Gateway Station | San Antonio Bus Station | Fastest | ||||
Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | Gateway Station | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Gateway Station | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Pearl District | No tags |
Last refresh of the prices: Yesterday at 7:57 PM CST.
Compare 2 ways to travel from St. Louis to San Antonio
Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 22 hours 30 minutes and with fares starting at just R 1 269, it presents an excellent value for a comfortable ride.
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Where are the popular stops in St. Louis and San Antonio?
Frequently asked questions about travelling from St. Louis to San Antonio, US by bus
How much does a bus ticket from St. Louis to San Antonio cost?
The bus ticket price from St. Louis to San Antonio starts at R 1 269. The best way to find cheap bus tickets from St. Louis to San Antonio is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from St. Louis to San Antonio?
The average travel time between St. Louis and San Antonio is around 22h 30m, although the fastest bus will take about 20h 55m. This is the time it takes to travel the 1278 km that separates the two cities.
How many daily bus connections are there between St. Louis and San Antonio?
The number of buses from St. Louis to San Antonio can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from St. Louis to San Antonio by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from St. Louis to San Antonio?
When taking the bus from St. Louis to San Antonio, you can travel comfortably and safely with Greyhound, FlixBus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to San Antonio, US was searched and found on 20 Nov 2025 with a price of R 1 855To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Antonio, US as early as possible.
You can expect to pay from R 1 855 to R 3 692 for a bus ticket from St. Louis to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 855, which is on 2025-11-20.
