Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | San Antonio Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. + Valley Transit | Bus | Gateway Station | San Antonio Bus Station | Fastest | ||||
Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | Gateway Station | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Gateway Station | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Pearl District | No tags |
Last refresh of the prices: Today at 2:04 AM CST.
Compare 2 ways to go from St. Louis to San Antonio
Among the sustainable travel choices, the Bus stands out as a good way to reach San Antonio. The journey takes about 23 hours 45 minutes, and with fares starting at just $140, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and San Antonio?
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Compare bus companies
Frequently asked questions about travelling from St. Louis to San Antonio, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to San Antonio?
The cheapest bus tickets from St. Louis to San Antonio start from $140. The average price for this route is around $244. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to San Antonio?
The average bus travel time from St. Louis to San Antonio is 23h 45m, covering a distance of 1275 km. The quickest bus can get you there in 22h 45m and is operated by Greyhound.
Which bus companies service the St. Louis to San Antonio route?
What are the earliest and latest departure times for the bus from St. Louis to San Antonio?
The earliest bus departs from St. Louis to San Antonio at 1:00am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to San Antonio?
A bus trip from St. Louis to San Antonio generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from St. Louis to San Antonio?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from St. Louis to San Antonio?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from St. Louis to San Antonio?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to San Antonio?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to San Antonio, US was searched and found on Jan 12, 2026 with a price of $164To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Antonio, US, as early as possible.
You can expect to pay from $164 to $340 for a bus ticket from St. Louis to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $164 which is on 2026-01-12.
