Based on 87398 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $64
Greyhound Chicago Des Moines recent customer reviews
Maybe it should be written in the details of the trip that we have to weigh our luggage.
Based on 759 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the seats but often complained with the WiFi. Jefferson Lines ticket prices on this trip start at $119
Based on 20 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Burlington Trailways ticket prices on this trip start at $85
Based on 11454 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $74
Frequently asked questions about travelling from Chicago to Des Moines by bus
What is the distance between Chicago and Des Moines?
Chicago and Des Moines are 496 km (308 miles) apart.
What are the departure and arrival locations for buses traveling from Chicago to Des Moines?
Buses departing from Downtown Greyhound Station in Chicago will take you to Jefferson/Trailways Depot in Des Moines.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-24
$116
11-25
$225
Today
$116
11-27
$117
11-28
$107
11-29
$103
11-30
$208
12-01
$94
The cheapest trip from Chicago to Des Moines was searched and found on Dec 1, 2025 with a price of $94
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Des Moines, as early as possible.
You can expect to pay from $94 to $225 for a bus ticket from Chicago to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-12-01.
Usually Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Chicago to Des Moines was searched and found on Dec 1, 2025 with a price of $94
