Find coaches from Chicago to Des Moines

Next departures

Next departures from Chicago to Des Moines on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		Chicago 95Th & Dan Ryan
    		Des MoinesCheapest
    Jefferson Lines
      		Chicago (Bus Station)
      		Des MoinesFastest
      Greyhound Lines, Inc.
        		Downtown Greyhound Station
        		Des MoinesNo tags
        FlixBus + Greyhound Lines, Inc.
          		Chicago 95Th & Dan Ryan
          		Des MoinesNo tags
          Greyhound Lines, Inc.
            		Downtown Greyhound Station
            		Des MoinesNo tags

            Last refresh of the prices: Today at 6:59 PM CST.

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            Get from Chicago to Des Moines

            This route is served by bus only

            The journey takes about 9 hours 10 minutes, and with fares starting at just US$34, it presents an excellent value for a comfortable ride.

            7bus per day
            9h 10mAverage duration
            496 kmDistance
            12kgCO₂ emissions

            Bus Chicago to Des Moines: Trip Overview

            Average ticket priceUS$53
            Average bus trip duration9h 10m
            Number of daily buses7
            Earliest bus departure04:45
            Distance496 km
            Latest bus departure23:50

            Chicago to Des Moines Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Des Moines.

            Bus service from Chicago to Des Moines will be provided by the most trusted bus companies.

            Whether it is cheap bus tickets or more luxurious buses going to Des Moines from Chicago, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions on the trip Chicago - Des Moines

            1. How much does a bus ticket from Chicago to Des Moines cost?

              The bus ticket price from Chicago to Des Moines starts at US$34. The best way to find cheap bus tickets from Chicago to Des Moines is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Chicago to Des Moines?

              The average travel time between Chicago and Des Moines is around 9h 10m, although the fastest bus will take about 7h 15m. This is the time it takes to travel the 496 km that separates the two cities.

            3. How many daily bus connections are there between Chicago and Des Moines?

              The number of buses from Chicago to Des Moines can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Chicago to Des Moines by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Chicago to Des Moines?

              When taking the bus from Chicago to Des Moines, you can travel comfortably and safely with Greyhound, Burlington Trailways, FlixBus.

            5. What are the departure and arrival stations when taking the bus from Chicago to Des Moines?

              Buses travelling between Chicago and Des Moines leave from Downtown Greyhound Station or Chicago O'Hare International Airport and arrive at Jefferson/Trailways Depot, 1514 East Grand Ave.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            US$59
            01/11
            US$59
            Today
            US$56
            03/11
            US$106
            04/11
            US$54
            05/11
            US$47
            06/11
            US$45
            07/11
            US$41
            busbud logoThe cheapest trip from Chicago to Des Moines was searched and found on 07 Nov 2025 with a price of US$41

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Des Moines as early as possible.

            You can expect to pay from US$41 to US$156 for a bus ticket from Chicago to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$41, which is on 2025-11-07.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Des Moines but it'll also be endearing to native speakers who will surely appreciate your effort.

            Much more than a mere vehicle taking you from Chicago to Des Moines, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Des Moines.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to Des Moines.

            Did you know?

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            Will you be returning to Chicago by bus?

            Bus from Des Moines to Chicago

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            Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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