Bus from Chicago to Des Moines: Tickets & Timetables

Next bus departures

Next departures from Chicago to Des Moines on 28 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Des MoinesCheapest
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Des MoinesFastest
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Des MoinesNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Des MoinesNo tags
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Des MoinesNo tags

Last refresh of the prices: Today at 06:20 CST.

Get from Chicago to Des Moines

This route is served by bus only

The journey takes about 9 hours 10 minutes, and with fares starting at just £35, it presents an excellent value for a comfortable ride.

8bus per day
9h 10mAverage duration
307 milesDistance
12kgCO₂ emissions

Frequently asked questions about travelling by bus from Chicago to Des Moines

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Chicago to Des Moines?

    The cheapest coach tickets from Chicago to Des Moines start from £35. The average price for this route is around £46. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Chicago to Des Moines?

    The average bus journey time from Chicago to Des Moines is 9h 10m, covering a distance of 307 miles. The fastest bus can take you there in 6h and is operated by Jefferson Lines.

  3. Which bus companies service the Chicago to Des Moines route?

    Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound, Jefferson Lines, Burlington Trailways, FlixBus.

  4. What is the earliest and latest departure time for the bus from Chicago to Des Moines?

    The earliest bus departs from Chicago to Des Moines at 04:45. And the latest bus departs at 23:50.

  5. What are the CO₂ emissions for the bus trip from Chicago to Des Moines?

    A bus journey from Chicago to Des Moines produces an estimated 12 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Chicago to Des Moines?

    According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.

  7. Which company has the best Wi-Fi from Chicago to Des Moines?

    Based on Busbud reviews, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

  8. Which bus company offers the most punctual service from Chicago to Des Moines?

    According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Chicago to Des Moines?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
25/11
£121
26/11
£62
Today
£61
28/11
£61
29/11
£63
30/11
£112
01/12
£54
02/12
£35
busbud logoThe cheapest trip from Chicago to Des Moines was searched and found on 2 Dec 2025 with a price of £35

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Des Moines as early as possible.

You can expect to pay from £35 to £121 for a bus ticket from Chicago to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at £35, which is on 2025-12-02.

Usually Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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