Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Orlando Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Tupelo (Brothers Quick Stop) | The Florida Mall | No tags | ||||
 | Bus | Tupelo (Brothers Quick Stop) | Orlando Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Orlando Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Tupelo (Brothers Quick Stop) | The Florida Mall | No tags |
Get from Tupelo to Orlando
The journey takes about 17 hours 55 minutes and with fares starting at just $79, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Lines, Inc. Tupelo Orlando recent customer reviews
The only problem I had was one of the buses bathroom door will not stay shut and I was seated right next to it and it stunk horribly
Paul H.
Frequently asked questions about traveling from Tupelo to Orlando by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Orlando was searched and found on Nov 27, 2025 with a price of $100To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Orlando, as early as possible.
You can expect to pay from $100 to $100 for a bus ticket from Tupelo to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $100 which is on 2025-11-27.
