Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | The Florida Mall | Cheapest | ||||
 | Bus | Tupelo (Brothers Quick Stop) | Orlando Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Orlando Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | The Florida Mall | No tags |
Last refresh of the prices: Today at 12:41 CST.
Get from Tupelo to Orlando
The journey takes about 17 hours 55 minutes, and with fares starting at just £104, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87503 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £106
Greyhound Lines, Inc. Tupelo Orlando recent customer reviews
The only problem I had was one of the buses bathroom door will not stay shut and I was seated right next to it and it stunk horribly
Paul H.
Frequently asked questions about travelling by bus from Tupelo to Orlando
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Tupelo to Orlando?
The cheapest coach tickets from Tupelo to Orlando start from £104. The average price for this route is around £125. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Tupelo to Orlando?
The average bus journey time from Tupelo to Orlando is 17h 55m, covering a distance of 581 miles. The fastest bus can take you there in 16h 5m and is operated by Greyhound.
Which bus companies service the Tupelo to Orlando route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Tupelo to Orlando?
The earliest bus departs from Tupelo to Orlando at 10:55. And the latest bus departs at 23:15.
What are the CO₂ emissions for the bus trip from Tupelo to Orlando?
A bus journey from Tupelo to Orlando produces an estimated 23 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Orlando was searched and found on 20 Jan 2026 with a price of £89To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Orlando as early as possible.
You can expect to pay from £89 to £102 for a bus ticket from Tupelo to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at £89, which is on 2026-01-20.
