Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Tampa Bus Station | Lake City Bus Station | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | University of South Florida | Lake City Bus Station | No tags |
Last refresh of the prices: Yesterday at 6:41 PM EST.
Get from Tampa to Lake City
This route is served by bus only
The journey takes about 10 hours 25 minutes and with fares starting at just $31, it presents an excellent value for a comfortable ride.
4bus per day
10h 25mAverage Duration
147 milesDistance
6kgCO₂ emissions
Where are the popular stops in Tampa and Lake City?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
Compare bus companies
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from Tampa to Lake City by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
No data
11/21
$68
Today
$69
11/23
$46
11/24
$32
11/25
$50
11/26
$52
11/27
No data
The cheapest trip from Tampa to Lake City was searched and found on Nov 24, 2025 with a price of $32To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Lake City, as early as possible.
You can expect to pay from $32 to $69 for a bus ticket from Tampa to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-11-24.
